Evidence map›Paper›PMID 41746321›Full record

ArticleAnalytical and bioanalytical chemistry2026

Fluorescent TAPY-bodipy dyads as tools for imaging fungal mitochondria by confocal microscopy and flow cytometry.

Jean C Neto, Rosa de Llanos, Francisco Galindo

Abstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jean C NetoDepartamento de Química Inorgánica y Orgánica, Universitat Jaume I de Castellón, Avda. Vicente Sos Baynat S/N, 12071, Castellón de La Plana, Spain.
Rosa de LlanosUnidad Predepartamental de Medicina, Universitat Jaume I de Castellón, Avda. Vicente Sos Baynat S/N, 12071, Castellón de La Plana, Spain.
Francisco GalindoDepartamento de Química Inorgánica y Orgánica, Universitat Jaume I de Castellón, Avda. Vicente Sos Baynat S/N, 12071, Castellón de La Plana, Spain. francisco.galindo@uji.es.ORCID http://orcid.org/0000-0003-0826-6084

Funding

Agencia Estatal de Investigación PID2024-162004OB-I00European Regional Development Fund PID2024-162004OB-I00Generalitat Valenciana CIAICO/2022/207Generalitat Valenciana GRISOLIAP/2021/064Ministerio de Ciencia, Innovación y Universidades PID2024-162004OB-I00
6 · The paper itself

Abstract

Mitochondria-targeted fluorescent probes are essential tools in cell biology, yet most have been optimized for mammalian cells rather than fungi, despite the growing clinical relevance of pathogenic yeasts. Here, we evaluate six triarylpyridinium-bodipy (TAPY-BDP) conjugates as mitochondrial markers in Candida albicans and Pichia kudriavzevii (formerly Candida krusei), using a triphenylphosphonium-bodipy (TPP-BDP) dyad and a non-targeted propyl-bodipy (prop-BDP) as references. Confocal microscopy and flow cytometry quantified uptake and localization. Colocalization with MitoTracker™ Deep Red gave Pearson correlation coefficients up to 0.9, supporting efficient targeting for most TAPY derivatives. TAPY-BDPs with R = H, Me, OMe, or NMe

Indexed as

Boron CompoundsCandida albicansFlow CytometryFluorescent DyesMitochondriaPichiaPyridinium CompoundsFluorescent Chemosensor CompoundsMicroscopy, Confocal4,4-difluoro-4-bora-3a,4a-diaza-s-indaceneBoron CompoundsFluorescent Chemosensor CompoundsFluorescent DyesPyridinium CompoundsBioanalysisCandida albicansCandida kruseiFlow cytometryFluorescenceFungiImagingMicroscopyMitochondriaTargetingYeast

Identifiers

PMID41746321
PMCPMC13079517

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.