Evidence map›Paper›PMID 41746490›Full record

ArticleClinical and experimental nephrology2026

Recent trends in dialysis initiation in Japan: a region‑specific descriptive analysis using Hokkaido as an example.

Hirofumi Sakuma, Megumi Matsumoto, Yusuke Kanno, Saeko Miura, Reina Suetsugu-Ishizawa, Nozomi Hayashi, Motoki Matsuki, Atsushi Wada, Naoki Nakagawa

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Article in Clinical and experimental nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Hirofumi SakumaDivision of Cardiology and Nephrology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Japan.
Megumi MatsumotoDivision of Cardiology and Nephrology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Japan.
Yusuke KannoDivision of Cardiology and Nephrology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Japan.
Saeko MiuraDivision of Cardiology and Nephrology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Japan.
Reina Suetsugu-IshizawaDivision of Cardiology and Nephrology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Japan.
Nozomi HayashiDivision of Cardiology and Nephrology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Japan.
Motoki MatsukiDivision of Cardiology and Nephrology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Japan.
Atsushi WadaDepartment of Nephrology, Kitasaito Hospital, Asahikawa, Japan.
Naoki NakagawaDivision of Cardiology and Nephrology, Department of Internal Medicine, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, Japan. naka-nao@asahikawa-med.ac.jp.ORCID http://orcid.org/0000-0002-5398-3667

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe increasing number of dialysis patients presents a significant public health challenge in Japan. While the number of patients initiating dialysis due to chronic glomerulonephritis (CGN) or diabetic kidney disease (DKD) has decreased, the incidence of dialysis initiation attributed to nephrosclerosis has gradually increased. To investigate regional differences, Hokkaido, Japan, was selected as one regional example in this study.

methodsData were extracted from a web-based national database for patients aged ≥ 40 years who initiated dialysis between 2012 and 2021. Patients were categorized according to sex, age, and underlying disease. Dialysis initiation rates were calculated as the number of new dialysis patients divided by the corresponding population. To assess temporal changes, the 2021/2016 ratio was calculated by dividing the initiation rate in 2021 by that in 2016 for each prefecture.

resultsIn Hokkaido, the dialysis initiation rates for DKD declined across all age groups, whereas the national rate increased in men aged ≥ 80 years. For nephrosclerosis, the initiation rates rose among older adults both nationally and in Hokkaido, although the increase in Hokkaido was more gradual. CGN-related rates decreased consistently across all age groups, both nationally and in Hokkaido. Prefectures with 2021/2016 ratio of ≥ 1 were more frequently observed among patients with nephrosclerosis than among those with CGN or DKD, especially among older populations.

conclusionsDialysis initiation rates in Hokkaido decreased in most subgroups compared with national trends. Given the rising incidence of nephrosclerosis among older adults, targeted interventions at the prefectural level are urgently warranted.

Indexed as

Diabetic NephropathiesGlomerulonephritisNephrosclerosisRenal DialysisAdultAgedAged, 80 and overAge DistributionDatabases, FactualFemaleHumansIncidenceJapanMaleMiddle AgedDiabetic kidney diseaseDialysis initiationJapanese registryNephrosclerosisRegional differences

Identifiers

PMID41746490
PMCPMC13009071

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.