ReviewInternational dental journal2026
Mesoporous Bioactive Glass: Preparation, Characterisation, and Emerging Applications in Regenerative Medicine and Dentistry.
Review in International dental journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Mesoporous Bioactive Glass Nanoparticle-Reinforced Calcium Silicate Sealer for Reduced Microleakage and Enhanced Antibacterial Performance.Journal of functional biomaterials · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
INTRODUCTION AND
aimsMesoporous bioactive glasses have emerged as advanced biomaterials due to their highly ordered mesoporous structure, large surface area, and enhanced biological reactivity. These properties distinguish them from conventional bioactive glasses and underpin their growing interest in regenerative medicine and dentistry. This review aims to summarise the development, synthesis, structural characteristics, and applications of mesoporous bioactive glasses, with a focus on their translational potential.
methodsA narrative review of the literature was conducted using major scientific databases to identify peer-reviewed studies related to the preparation, characterisation, and biomedical and dental applications of mesoporous bioactive glasses. Relevant in vitro and in vivo studies were critically analysed to synthesise current evidence and emerging trends.
resultsMesoporous bioactive glasses exhibit tunable pore sizes, high surface area, and enhanced ion and drug release capabilities, resulting in rapid hydroxyapatite formation and improved cell adhesion and proliferation. Various synthesis approaches, including sol-gel and templating techniques, allow precise control over composition and mesostructure. Reported applications include bone and soft tissue regeneration, drug delivery, wound healing, and antimicrobial therapies. In dentistry, mesoporous bioactive glasses have been explored for enamel remineralisation, periodontal regeneration, dentin hypersensitivity management, orthodontic applications, endodontic therapy, and implant surface modification. Most evidence remains pre-clinical.
conclusionMesoporous bioactive glasses have emerged as a promising class of biomaterials for regenerative and dental applications. However, limitations related to mechanical strength, manufacturing scalability, and the lack of clinical studies currently restrict widespread clinical applications. CLINICAL RELEVANCE: Mesoporous bioactive glasses offer enhanced bioactivity and therapeutic delivery compared with conventional bioactive glasses, highlighting their potential to improve regenerative and restorative dental outcomes once translational challenges are addressed.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.