Trial reportPsychoneuroendocrinology2026
A randomized trial of prenatal cognitive behavioral stress management effects on obstetric health outcomes and infant cortisol levels.
Trial report in Psychoneuroendocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
backgroundAltered cortisol patterns during pregnancy have been linked to heightened risk for obstetric health complications (e.g., low infant birthweight) and dysregulated infant cortisol levels after birth, particularly in chronically stressed, low-income and ethnic minority families. Considering the detrimental effects that dysregulated cortisol may have on maternal and infant health, prenatal interventions aimed at cortisol regulation in at-risk families are needed. In a previous study, we reported that low-income, ethnic minority pregnant women randomized to a prenatal cognitive behavioral stress management (CBSM) intervention showed improved pre- and postnatal stress and salivary cortisol patterns relative to a control group. The current study extends this work by investigating whether families who received this prenatal CBSM intervention, relative to a control group, experienced fewer obstetric health complications and more regulated infant post partum cortisol patterns, and if maternal cortisol patterns and psychosocial factors (stressful life events, resilience) influenced CBSM intervention effects.
methodsOne hundred pregnant women (76 % annual income < $20 K, <17 weeks of gestation) were randomized to an eight-week CBSM group intervention (n = 55) or a control group (n = 45). Salivary cortisol was collected at baseline (1st trimester), after the intervention (3rd trimester), and at three months post partum (mothers and infants). Obstetric health complications were assessed via a medical record review.
resultsPrenatal CBSM (compared to the control group) showed fewer obstetric health complications for mothers with elevated prenatal cortisol levels. Further, CBSM (compared to the control group) showed more regulated cortisol patterns (i.e., reducing total cortisol, steeper decline in diurnal cortisol) for infants of mothers who had high cortisol and stress levels, and for infants of African American mothers.
conclusionsThese results lend support to the effectiveness of prenatal CBSM in enhancing the health of low-income, ethnic minority mothers and their infants, and emphasize the need to investigate the prolonged impact of CBSM in community-based settings.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.