Evidence map›Paper›PMID 41747712›Full record

ArticleCartilage2026

Quantitative Magnetic Resonance Spectroscopy and T2 Mapping for Evaluating Knee Subchondral Bone and Cartilage Changes in Chronic Kidney Disease.

Shih-Wei Chiang, Yu-Juei Hsu, Yi-Jen Peng, Yi-Chih Hsu, Skye Hsin-Hsien Yeh, Yu-Ching Chou, Herng-Sheng Lee, Ying-Chun Liu, Chao-Ying Wang, Guo-Shu Huang

Abstract read
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In one paragraph

Article in Cartilage, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shih-Wei ChiangDepartment of Radiology, Tri-Service General Hospital, National Defense Medical University, Taipei.ORCID 0000-0002-9672-1077
Yu-Juei HsuDivision of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei.
Yi-Jen PengDepartment of Pathology, Tri-Service General Hospital, National Defense Medical University, Taipei.
Yi-Chih HsuDepartment of Radiology, Tri-Service General Hospital, National Defense Medical University, Taipei.
Skye Hsin-Hsien YehBrain Research Center, School of Medicine, National Defense Medical University, Taipei.
Yu-Ching ChouSchool of Public Health, National Defense Medical University, Taipei.
Herng-Sheng LeeDivision of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical University, Taipei.
Ying-Chun LiuDepartment of Radiology, Tri-Service General Hospital, National Defense Medical University, Taipei.
Chao-Ying WangGraduate Institute of Biology and Anatomy, College of Medicine, National Defense Medical University, Taipei.
Guo-Shu HuangDepartment of Radiology, Tri-Service General Hospital, National Defense Medical University, Taipei.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveTo investigate water and lipid composition changes in knee subchondral bone marrow and cartilage in chronic kidney disease (CKD) patients compared with age- and sex-matched healthy controls using magnetic resonance spectroscopy (MRS) and T2 mapping.DesignThis IRB-approved case-control study included 20 CKD patients (12 men, 8 women) and 20 age- and sex-matched healthy controls (10 men, 10 women). MRS and T2 measurements were performed on regions of interest in the knee subchondral bone and cartilage. Water content, lipid composition, fat content, and the unsaturation index (UI) were quantified using LCModel. Differences between groups were assessed using independent samples

Indexed as

cartilagechronic kidney diseaseknee subchondral bonemagnetic resonance spectroscopyT2 mapping

Identifiers

PMID41747712
PMCPMC12945744

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.