ReviewCell death discovery2026
Endometriosis immune microenvironment timing shifts: from immune escape to immune exhaustion.
Review in Cell death discovery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Deciphering immune-inflammatory dysregulation in the endometriotic microenvironment: insights from single-cell omics and artificial intelligence.Frontiers in immunology · 2026Review
- Immune-epigenetic-metabolic crosstalk: attempting to unravel the multidimensional mechanisms of immune evasion in endometriosis.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Endometriosis(EMS) symptoms, progression, and onset are all linked to the patient's immune system dysfunction. Research on immune cells and their molecular mechanisms has long been a prime focus of EMS studies. Nonetheless, the immune environments of EMS patients and cells are constantly changing. How to effectively study and treat EMS depends on our ability to comprehend the temporal changes in immunity in EMS patients. Consequently, the immunological time sequence of endometriosis is methodically discussed and summarized in this article as four steps: 1) immune escape, in which Ectopic Endometrial Cells(EECs) evade immune surveillance and growth in the peritoneum; 2) pro-inflammatory immune response, immune killer cells are triggered, and the lesions show signs of inflammation; 3) immunological anti-inflammatory, which converts pro-inflammatory micro-environment to anti-inflammatory micro-environment and helps the body avoid excessive inflammation; 4) Immune exhaustion: Immune killer cells gradually lose their ability to attack EECs as they experience exhaustion and paralysis. In addition to providing a reference for future EMS staging treatments, this study offers a comprehensive understanding of the temporal alterations in EMS. It reveals cellular and molecular processes associated with immune exhaustion.
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.