ArticleNPJ biofilms and microbiomes2026
Classification of the tongue microbiota and its associations with lifestyle factors and health status.
Article in NPJ biofilms and microbiomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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11 authors.
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Abstract
The oral microbiota plays a vital role in human health, yet most studies have focused on individual bacterial taxa. To provide a more comprehensive understanding, we analyzed tongue microbiota data from 729 Japanese individuals and classified samples into three types (orotypes): Neisseria-dominant (N), Prevotella-dominant (P), and Streptococcus-dominant (S) types. Each orotype exhibited distinct co-occurrence network structures and was associated with lifestyle factors such as oral care, diet, and smoking. The S type was associated with higher odds of abnormal oral health and metabolic syndrome-related outcomes compared to the N type. In addition, we developed a robust classification model (ROC-AUC > 0.95) to predict orotypes, which showed temporal stability in nearly half of individuals over a 6-year period. These findings highlight the value of orotype classification for monitoring tongue microbial communities and suggest its potential in health risk assessment.
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