Evidence mapPaperPMID 41748974Full record

ReviewApplied microbiology and biotechnology2026

Nanoparticle-based approaches for bacterial detection and therapy.

Vinod Kumar Rajana, Anuradha Matireddy, Jeevan Miriyals, Kaki Yamini Naga Lakshmi, Keerthi Pallavi, Kokkeragadda Hasini, Sohitha Sruthi

Abstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Zinc oxide-bacteriophage synergistic combination for dual-mode antibacterial activity against multidrug-resistant Escherichia coli.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vinod Kumar RajanaDepartment of Pharmaceutics, Shri Vishnu College of Pharmacy, Bhimavaram, 534202, Andhra Pradesh, India. vinoddhniper@gmail.com.
Anuradha Matireddy *Department of Pharmaceutics, Shri Vishnu College of Pharmacy, Bhimavaram, 534202, Andhra Pradesh, India.
Jeevan Miriyals *Department of Pharmaceutics, Shri Vishnu College of Pharmacy, Bhimavaram, 534202, Andhra Pradesh, India.
Kaki Yamini Naga LakshmiDepartment of Pharmaceutics, Shri Vishnu College of Pharmacy, Bhimavaram, 534202, Andhra Pradesh, India.
Keerthi PallaviDepartment of Pharmaceutics, Shri Vishnu College of Pharmacy, Bhimavaram, 534202, Andhra Pradesh, India.
Kokkeragadda HasiniDepartment of Pharmaceutics, Shri Vishnu College of Pharmacy, Bhimavaram, 534202, Andhra Pradesh, India.
Sohitha SruthiDepartment of Pharmaceutics, Shri Vishnu College of Pharmacy, Bhimavaram, 534202, Andhra Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The advent of nanotechnology has revolutionised approaches to identifying and combating bacterial infections. This review highlights the latest applications of nanoparticles (NPs) for bacterial detection and treatment, with a focus on their translational potential in clinical settings. We discuss advanced nanotechnology-enabled biosensing platforms that offer ultra-sensitive, rapid and precise diagnostics capabilities crucial for addressing antibiotic-resistant pathogens. In addition to detection, various nanoparticles demonstrate multiple antibacterial mechanisms and function as targeted drug-delivery vehicles. The review also examines current clinical trials involving nanoparticle-based therapeutics, underscoring their promise for overcoming antimicrobial resistance. KEY POINTS: • Nanoparticles enable rapid and sensitive detection of bacterial infections. • Multiple antibacterial mechanisms improve efficacy against resistant pathogens. • Translational challenges must be addressed for successful clinical application.

Indexed as

Anti-Bacterial AgentsBacteriaBacterial InfectionsBiosensing TechniquesNanoparticlesDrug Delivery SystemsDrug Resistance, BacterialHumansNanotechnologyAnti-Bacterial AgentsAntibacterial activityAntimicrobial resistanceBiosensorsClinical translationDrug deliveryNanoparticles

Identifiers

PMID41748974
PMCPMC12948857

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.