Evidence map›Paper›PMID 41749505›Full record

ArticleJournal of natural products2026

Gigobolins A-C, New Ophiobolins with Anticancer Activity from the Phytopathogenic Fungus

Marianna Carbone, Sridharan Jayamohan, Amelia Scott, Angela Boari, Ryan J Rutledge, Nadia Cacciapuoti, Vamika Gautam, Jaquelin Aroujo, Tania Betancourt, Daniel Romo and 5 more

Abstract read
In one paragraph

Article in Journal of natural products, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Marianna CarboneNational Research Council (CNR), Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.
Sridharan JayamohanDepartment of Obstetrics and Gynecology, University of Texas Health San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States.
Amelia ScottDepartment of Chemistry and Biochemistry, Texas State University, 601 University Dr., San Marcos, Texas 78666, United States.
Angela BoariNational Research Council, Institute of Sciences of Food Production, Via Amendola 122/O, 70125 Bari, Italy.
Ryan J RutledgeDepartment of Chemistry and Biochemistry, Texas State University, 601 University Dr., San Marcos, Texas 78666, United States.
Nadia CacciapuotiNational Research Council (CNR), Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.
Vamika GautamDepartment of Biology, Baylor University, 101 Bagby Ave., Waco, Texas 76798, United States.
Jaquelin AroujoDepartment of Chemistry and Biochemistry, Baylor University, 101 Bagby Ave., Waco, Texas 76798, United States.
Tania BetancourtDepartment of Chemistry and Biochemistry, Texas State University, 601 University Dr., San Marcos, Texas 78666, United States.ORCID 0000-0002-2460-6133
Daniel RomoDepartment of Chemistry and Biochemistry, Baylor University, 101 Bagby Ave., Waco, Texas 76798, United States.ORCID 0000-0003-3805-092X
Gangadhara Reddy SareddyDepartment of Obstetrics and Gynecology, University of Texas Health San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States.ORCID 0000-0001-9977-3932
Joseph H TaubeDepartment of Biology, Baylor University, 101 Bagby Ave., Waco, Texas 76798, United States.
Alexander KornienkoDepartment of Chemistry and Biochemistry, Texas State University, 601 University Dr., San Marcos, Texas 78666, United States.ORCID 0000-0003-2041-7367
Antonio EvidenteNational Research Council (CNR), Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.ORCID 0000-0001-9110-1656
Maria Letizia CiavattaNational Research Council (CNR), Institute of Biomolecular Chemistry, Via Campi Flegrei 34, 80078 Pozzuoli, Italy.ORCID 0000-0002-7308-1011

Funding

Pharmacophore-Directed  Retrosynthesis Applied to Bioactive Natural Products Informing Mechanism of Action StudiesR35GM134910 · NIGMS · BAYLOR UNIVERSITY · PI DANIEL ROMO · 2020 to 2026
$2.7M
NIGMS NIH HHS R35 GM134910
6 · The paper itself

Abstract

Three new sesterterpenoids, gigobolins A to C (

Indexed as

Antineoplastic AgentsAscomycotaSesterterpenesCell Line, TumorDrug Screening Assays, AntitumorFemaleHumansMolecular StructureAntineoplastic AgentsophiobolinsSesterterpenes

Identifiers

PMID41749505
PMCPMC13036769

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.