ReviewChildren (Basel, Switzerland)2026
Advantages of Ciprofol with Special Consideration of Pediatric Anesthesia.
Alessandro Vittori, Cecilia Di Fabio, Marco Cascella, Franco Marinangeli, Elisa Francia, Ilaria Mascilini, Cecilia Maria Pizzo, Corrado Cecchetti, Valentina Di Conza, Teresa Grimaldi Capitello and 3 more
Abstract readReview
In one paragraphReview in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
13 authors.
Alessandro VittoriDepartment of Anesthesia, Critical Care and Pain Medicine, ARCO, Ospedale Pediatrico Bambino Gesù IRCCS, Piazza S. Onofrio 4, 00165 Rome, Italy.ORCID 0000-0002-2377-3765 Cecilia Di FabioDepartment of Life, Health and Environmental Sciences (MeSVA), University of L'Aquila, Piazzale Salvatore Tommasi 1, Blocco 11, Coppito, 67010 L'Aquila, Italy.
Marco CascellaDepartment of Medicine, Surgery and Dentistry, University of Salerno, Via Salvador Allende, 43, 84081 Baronissi, Italy.ORCID 0000-0002-5236-3132 Franco MarinangeliDepartment of Life, Health and Environmental Sciences (MeSVA), University of L'Aquila, Piazzale Salvatore Tommasi 1, Blocco 11, Coppito, 67010 L'Aquila, Italy.ORCID 0000-0002-4931-7717 Elisa FranciaDepartment of Anesthesia, Critical Care and Pain Medicine, ARCO, Ospedale Pediatrico Bambino Gesù IRCCS, Piazza S. Onofrio 4, 00165 Rome, Italy.ORCID 0000-0003-1732-2391 Ilaria MasciliniDepartment of Anesthesia, Critical Care and Pain Medicine, ARCO, Ospedale Pediatrico Bambino Gesù IRCCS, Piazza S. Onofrio 4, 00165 Rome, Italy.ORCID 0000-0002-6484-8436 Cecilia Maria PizzoDepartment of Anesthesia, Critical Care and Pain Medicine, ARCO, Ospedale Pediatrico Bambino Gesù IRCCS, Piazza S. Onofrio 4, 00165 Rome, Italy.
Corrado CecchettiDepartment of Anesthesia, Critical Care and Pain Medicine, ARCO, Ospedale Pediatrico Bambino Gesù IRCCS, Piazza S. Onofrio 4, 00165 Rome, Italy.
Valentina Di ConzaDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 5, 80131 Naples, Italy.
Teresa Grimaldi CapitelloClinical Psychology Unit, Department of Neuroscience, Ospedale Pediatrico Bambino Gesù IRCCS, Piazza S. Onofrio 4, 00165 Rome, Italy.ORCID 0000-0002-5613-912X Giuseppe ServilloDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 5, 80131 Naples, Italy.
Pasquale BuonannoDepartment of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples "Federico II", Via Pansini, 5, 80131 Naples, Italy.ORCID 0000-0001-7933-6209 Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
The search for an ideal anesthetic has always been a major goal in anesthesiology. In recent years, the introduction of ciprofol has marked a major breakthrough in the pharmacological field, following the introduction of dexmedetomidine. Ciprofol has similar characteristics to propofol but with greater hemodynamic stability. Furthermore, it overcomes one of the most common discomforts associated with propofol: pain at the injection site. These characteristics make it a suitable hypnotic for pediatric use. Although studies on children are still limited, the literature on adults is now substantial and of high quality. The potential advantages of using ciprofol in pediatric anesthesia include pain-free induction, hemodynamic stability, less respiratory depression, and a lower incidence of emergence delirium.
Indexed as
anesthesiachildrencipepofolciprofolemergence deliriumHSK3486opioidpainpediatric anesthesia
Identifiers
PMID41749542
PMCPMC12939459
What Socratic holds
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