Evidence map›Paper›PMID 41749683›Full record

ReviewBioengineering (Basel, Switzerland)2026

Next-Gen Restorative Materials to Revolutionise Smiles.

John Yun Niu, Kelsey Xingyun Ge, Iris Xiaoxue Yin, Olivia Lili Zhang, Irene Shuping Zhao, Chun Hung Chu

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

John Yun NiuFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-3471-180X
Kelsey Xingyun GeSchool of Dentistry, Shenzhen University, Shenzhen 518055, China.
Iris Xiaoxue YinFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0003-1167-2999
Olivia Lili ZhangFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.
Irene Shuping ZhaoSchool of Dentistry, Shenzhen University, Shenzhen 518055, China.
Chun Hung ChuFaculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.ORCID 0000-0002-8167-0430

Funding

HMRF Research Fellowship Scheme 09230257
6 · The paper itself

Abstract

Recent breakthroughs in materials science have driven transformative advancements in restorative dentistry. Advanced dental materials, such as bioactive materials, nanocomposites, and fibre-reinforced composites, are attracting attention. Bioactive materials, such as calcium silicate-based cements and bioactive glass, represent a paradigm shift by interacting with biological tissues to stimulate regeneration. They promote hydroxyapatite formation, accelerating mineralisation in hard and soft tissues, and are pivotal tools in minimally invasive procedures due to their functions of structural support and biological interaction. Nanomaterials, especially nanocomposites with embedded nanoparticles, effectively address polymerisation shrinkage and wear in traditional composites. With just 1.5% shrinkage, a flexural strength over 150 MPa, and 44-60% higher wear resistance than conventional composites, they offer significant improvements. Nanocomposites also provide enamel-like translucency and a bond strength of 27-38 MPa to dentin, ensuring excellent aesthetics and durability-making them ideal for direct restorations. Fibre-reinforced composites with glass or polymer fibres balance aesthetics with strength and are increasingly used in restorations. Their high fracture resistance, which closely approaches that of a natural tooth, enables clinicians to preserve more healthy teeth during restoration, in line with the principles of modern conservative dentistry. Overall, bioactive materials enhance tissue repair, nanocomposites optimise form and function, and fibre-reinforced composites deliver strength without compromising aesthetics. As these materials transition from research to clinical practice, they promise longer-lasting treatments, fewer complications, and higher patient satisfaction. This narrative review aims to explore three types of advanced dental materials and their role in improving clinical outcomes.

Indexed as

bioactivecariescompositenanomaterialsnanoparticlesrestoration

Identifiers

PMID41749683
PMCPMC12937712

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.