Evidence mapPaperPMID 41749784Full record

ReviewBioengineering (Basel, Switzerland)2026

Laser Therapy in Basal Cell Carcinoma: Current Evidence, Literature Gaps and Future Perspectives.

Alessandro Clementi, Giovanni Cannarozzo, Luca Guarino, Luca Gargano, Martina Tolone, Elena Zappia, Marco Gratteri, Annunziata Dattola, Caterina Longo, Giovanni Pellacani and 1 more

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alessandro ClementiDepartment of Clinical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0009-0003-7001-7756
Giovanni CannarozzoDepartment of Clinical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
Luca GuarinoDepartment of Clinical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0009-0002-9678-6409
Luca GarganoDepartment of Clinical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0009-0006-0727-8314
Martina ToloneDepartment of Clinical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-8216-1550
Elena ZappiaDepartment of Clinical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0009-0005-8167-0325
Marco GratteriDepartment of Plastic, Reconstructive and Cosmetic Surgery, Campus Bio-Medico University Hospital, 00128 Rome, Italy.ORCID 0000-0001-7375-1524
Annunziata DattolaDepartment of Clinical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
Caterina LongoDepartment of Dermatology, University of Modena and Reggio Emilia, 41124 Modena, Italy.ORCID 0000-0002-8218-3896
Giovanni PellacaniDepartment of Clinical Sciences, Sapienza University of Rome, 00185 Rome, Italy.
Steven Paul NisticòDepartment of Clinical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-3828-0883

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Basal cell carcinoma (BCC) is the most frequent skin cancer, and surgery remains the treatment of choice, particularly in high-risk subtypes and sites. However, in low-risk cases and in patients where cosmetic outcome is a priority, alternative strategies, including laser therapy, have been proposed. Different laser sources offer potential advantages in terms of minimal invasiveness, healing time, and cosmetic outcome, but their clinical role remains a matter of debate. This narrative review critically analyses the available evidence on the use of lasers in the treatment of basal cell carcinoma, with a focus on ablative lasers, vascular lasers, and laser-assisted photodynamic therapy. Mechanisms of action, main clinical results, limitations, and the emerging contribution of non-invasive imaging for case selection and response monitoring are discussed. Ablative lasers, in particular CO

Indexed as

basal cell carcinomaCO2 laserfractional laserlaser therapyNd:YAG laserphotodynamic therapypulsed dye laser

Identifiers

PMID41749784
PMCPMC12938791

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.