Evidence map›Paper›PMID 41749853›Full record

ArticleCancers2026

Targeting STAT3 Promotes Tumor Cell Death and Enhances T-Cell Activity in HPV16-Positive Cancer.

Ruben Prins, Daniel J Fernandez, Diane M Da Silva, James Turkson, De-Chen Lin, W Martin Kast

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruben PrinsDepartment of Immunology & Immune Therapeutics, USC/Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA.ORCID 0000-0003-0831-4189
Daniel J FernandezDepartment of Immunology & Immune Therapeutics, USC/Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA.
Diane M Da SilvaDepartment of Obstetrics & Gynecology, USC/Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA.
James TurksonDivision of Medical Oncology, Department of Medicine at Cedars-Sinai, Los Angeles, CA 90048, USA.ORCID 0000-0002-6964-1602
De-Chen LinCenter for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA.
W Martin KastDepartment of Immunology & Immune Therapeutics, USC/Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA.ORCID 0000-0003-2321-3159

Funding

VLP VACCINES AGAINST HPV INDUCED TUMORSR01CA074397 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI KAST, WIJBE MARTIN · 1997 to 2020
$5.5M
NIH HHS R01 CA074397
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cervical cancerCPA-7head and neck cancerHPVSTAT3T-cell immunity

Identifiers

PMID41749853
PMCPMC12940059

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.