Evidence mapPaperPMID 41749921Full record

ReviewCancers2026

Advancing the Study of Glioblastoma Through 3D Tumor Models.

Karen Salmeron-Moreno, Josephine Buclez, Chris Donghyun Kim, Karthik Papisetty, Thomas McCaffery, Fadi Jacob, Rommi Kashlan, Hithardhi Duggireddy, Karthik Valiveti, Justin Maldonado and 2 more

Abstract readReview
In one paragraph

Review in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Karen Salmeron-MorenoDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0003-0555-0063
Josephine BuclezDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.
Chris Donghyun KimDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.
Karthik PapisettyDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.
Thomas McCafferyDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.
Fadi JacobDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.
Rommi KashlanDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.
Hithardhi DuggireddyDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.ORCID 0009-0001-7628-8851
Karthik ValivetiDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.
Justin MaldonadoDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.
Gustavo PradillaDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0002-3661-3269
Tomas Garzon-MuvdiDepartment of Neurological Surgery, Emory University, Atlanta, GA 30322, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioblastoma (GBM), the most aggressive primary brain malignancy, remains a challenge to experimentally model. Accurately modeling the intra- and intertumoral heterogeneity of GBMs is essential for enhancing the predictive power of preclinical models and improving the effectiveness of current therapies. This review highlights recent advances in 3D tumor modeling, which accurately replicate the structural, cellular, and biochemical complexity of GBMs. We examine their translational potential and discuss current barriers to clinical translation.

Indexed as

3D systemsbioprintingcancerglioblastomaorganoidsspheroidstumor microenvironmenttumor-on-a-chip

Identifiers

PMID41749921
PMCPMC12939352

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.