Evidence map›Paper›PMID 41750316›Full record

ReviewBiomolecules2026

The Landscape of SERCA2 in Cardiovascular Diseases: Expression Regulation, Therapeutic Applications, and Emerging Roles.

Jianmin Wu, Mengting Liao, Tengkun Dai, Guiyan Liu, Jiayi Zhang, Yiling Zhu, Lin Xu, Juanjuan Zhao

Abstract readReview
In one paragraph

Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jianmin WuDepartment of Immunology, Zunyi Medical University, Zunyi 563000, China.
Mengting LiaoDepartment of Immunology, Zunyi Medical University, Zunyi 563000, China.
Tengkun DaiDepartment of Immunology, Zunyi Medical University, Zunyi 563000, China.
Guiyan LiuDepartment of Immunology, Zunyi Medical University, Zunyi 563000, China.
Jiayi ZhangDepartment of Immunology, Zunyi Medical University, Zunyi 563000, China.
Yiling ZhuDepartment of Immunology, Zunyi Medical University, Zunyi 563000, China.
Lin XuDepartment of Immunology, Zunyi Medical University, Zunyi 563000, China.
Juanjuan ZhaoDepartment of Immunology, Zunyi Medical University, Zunyi 563000, China.ORCID 0000-0001-9253-8083

Funding

National Natural Science Foundation of China 82272812, 82360018, 8250035488
6 · The paper itself

Abstract

Driven by rapid socioeconomic progress and changing lifestyles, the global burden of cardiovascular diseases (CVDs) continues to escalate, with surging morbidity and mortality rates imposing a severe threat to public health. Clinical treatments are focused on the alleviation of treatments, highlighting the need for a deeper understanding of CVDs pathogenesis and the development of targeted therapies. Recent studies have identified imbalances in intracellular Ca

Indexed as

Cardiovascular DiseasesSarcoplasmic Reticulum Calcium-Transporting ATPasesAnimalsCalciumGene Expression RegulationHumansProtein Processing, Post-TranslationalATP2A2 protein, humanCalciumSarcoplasmic Reticulum Calcium-Transporting ATPasescardiovascular diseaseexpression regulationSERCA2therapeutic targets

Identifiers

PMID41750316
PMCPMC12938818

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.