Evidence map›Paper›PMID 41750332›Full record

ArticleBiomolecules2026

Structural and Biophysical Analyses of Human Prostamide/Prostaglandin F Synthase with Two Active Form-Mimicking Mutations.

Sang Won Cheon, Yen Thi Kim Nguyen, Jin Mo Kang, Youngbeom Yu, Yoonyoung Heo, Hyoun Sook Kim, Byung Woo Han

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sang Won CheonResearch Institute of Pharmaceutical Sciences & Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0009-0009-6891-6414
Yen Thi Kim NguyenResearch Institute of Pharmaceutical Sciences & Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-6424-4168
Jin Mo KangResearch Institute of Pharmaceutical Sciences & Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0009-0005-4065-0408
Youngbeom YuResearch Institute of Pharmaceutical Sciences & Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0009-0009-3494-9170
Yoonyoung HeoResearch Institute, National Cancer Center, Goyang 10408, Republic of Korea.
Hyoun Sook KimResearch Institute, National Cancer Center, Goyang 10408, Republic of Korea.ORCID 0000-0003-1095-6463
Byung Woo HanResearch Institute of Pharmaceutical Sciences & Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-7571-3791

Funding

Korea Health Industry Development Institute RS-2023-KH141172National Research Foundation of Korea RS-2023-00218543
6 · The paper itself

Abstract

Human prostamide/prostaglandin F synthase (PGFS) catalyzes the NADPH-dependent conversion of prostaglandin H

Indexed as

Hydroxyprostaglandin DehydrogenasesMutationCatalytic DomainCrystallography, X-RayHumansMolecular Dynamics SimulationProtein ConformationHydroxyprostaglandin Dehydrogenasesprostaglandin-F synthaseCXXC motifprostaglandin F2αprostamide/prostaglandin F synthasethioredoxin fold-containing protein

Identifiers

PMID41750332
PMCPMC12938796

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.