ReviewBiomolecules2026
Extracellular Vesicles: A Multidimensional Role in the Occurrence and Development of Nasopharyngeal Carcinoma.
Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extracellular vesicles (EVs) have garnered significant attention in cancer research, as they enable the regulation of the occurrence, progression, and metastasis of tumors. This narrative review summarizes studies published between 2020 and 2025 from PubMed, focusing on nasopharyngeal carcinoma and extracellular vesicles. We analyze the function and mechanism of EVs in the tumor microenvironment, biomarkers, and treatment. Numerous studies have attempted to explain the mechanism of NPC-EVs affecting tumor microenvironments through the transmission of its cargo. And liquid-biopsy technology using EVs as biomarkers, such as exosomal cyclophilin A, the phosphatase and tensin homolog, and EVs-miR-30a-5p, has been studied for diagnosis and prognostic evaluation. In the therapy aspect, researchers are attempting to explore the role of EVs in the resistance process of NPC treatment, with the aim of clinical translation. Current limitations include biological distribution of EVs and so on. Future research should focus on establishing the standardized production system and more convenient separation and purification techniques for EVs. This review provides a comprehensive overview of the nasopharyngeal carcinoma-related EVs.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.