Evidence map›Paper›PMID 41750368›Full record

ArticleBiomolecules2026

Regulation of Phosphatidylinositol Synthesis in Human Primordial Placenta.

Bence Kovács, Zoltán Erdélyi, Gergely Asbóth, Gábor Gimes, Balázs Mészáros, Zsófia Erdélyi, Tamás Marton, Nándor Ács, Dorina Supák, Sándor Valent and 1 more

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In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Bence KovácsDepartment of Obstetrics and Gynecology, Semmelweis University, Üllői út 78/a, 1082 Budapest, Hungary.
Zoltán ErdélyiInstitute of Pharmacogenetics, University Hospital Essen, 1085 Essen, Germany.
Gergely AsbóthDepartment of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, Tűzoltó u. 37-47, 1093 Budapest, Hungary.
Gábor GimesDepartment of Obstetrics and Gynecology, Semmelweis University, Üllői út 78/a, 1082 Budapest, Hungary.
Balázs MészárosDepartment of Obstetrics and Gynecology, Semmelweis University, Üllői út 78/a, 1082 Budapest, Hungary.
Zsófia ErdélyiDepartment of Obstetrics and Gynecology, Semmelweis University, Üllői út 78/a, 1082 Budapest, Hungary.
Tamás MartonDepartment of Obstetrics and Gynecology, Semmelweis University, Üllői út 78/a, 1082 Budapest, Hungary.ORCID 0000-0001-5585-2276
Nándor ÁcsDepartment of Obstetrics and Gynecology, Semmelweis University, Üllői út 78/a, 1082 Budapest, Hungary.
Dorina SupákDepartment of Obstetrics and Gynecology, Semmelweis University, Üllői út 78/a, 1082 Budapest, Hungary.
Sándor ValentDepartment of Obstetrics and Gynecology, Semmelweis University, Üllői út 78/a, 1082 Budapest, Hungary.ORCID 0000-0003-1098-1861
Zoltán KukorDepartment of Molecular Biology, Institute of Biochemistry and Molecular Biology, Semmelweis University, Tűzoltó u. 37-47, 1093 Budapest, Hungary.

Funding

Hungarian Ministry for Culture and Innovation from the source of the National Research, Development and Innovation Fund 2024-1.2.3-HU-RIZONT-2024-00062
6 · The paper itself

Abstract

Phosphatidylinositol and its derivatives are essential components of cell membranes and play pivotal roles in growth signaling pathways. In the human primordial placenta, phosphatidylinositol synthesis is catalyzed by phosphatidylinositol synthase (PIS) and the phosphatidylinositol-exchange enzyme (IE), both of which require divalent cations. We investigated whether GTP-binding proteins modulate this biosynthetic process. Incorporation of [

Indexed as

PhosphatidylinositolsPlacentaFemaleGTP-Binding ProteinsHumansPregnancyTrophoblastsGTP-Binding ProteinsPhosphatidylinositolsG proteinhuman primordial placentaphosphatidylinositol synthesissignal transduction

Identifiers

PMID41750368
PMCPMC12937943

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.