Evidence mapPaperPMID 41750625Full record

ArticleAntioxidants (Basel, Switzerland)2026

Dietary Lycopene Mitigates Reproductive Impairment in Heat-Stressed Rongchang Boars: Roles of Antioxidant, Anti-Inflammatory and Nrf2 Pathway.

Ying Lei, Hanxin Liu, Qiujin Xiang, Ying Liu, De Wu, Junjie Zhang, Yan Lin

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying LeiCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.ORCID 0009-0007-0345-2511
Hanxin LiuCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.
Qiujin XiangCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.
Ying LiuCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.
De WuAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.
Junjie ZhangCollege of Life Science, Sichuan Agricultural University, Ya'an 625014, China.ORCID 0000-0002-4781-6862
Yan LinAnimal Nutrition Institute, Sichuan Agricultural University, Chengdu 611130, China.

Funding

National 14th Five-Year Plan Key R&D Projects 2023YFD1300804National Modern Agricultural Industry Technology System Sichuan Pig innovation team SCSZTD-2024-08National Natural Science Foundation of China 32272911National Natural Science Foundation of China 32573270Sichuan Province "14th Five-Year" Sichuan Pig Major Science and Technology Project 2021ZDZX0009Strategic Priority Research Program of the National Center of Technology Innovation for Pigs NCTIPXD/B04
6 · The paper itself

Abstract

Heat stress (HS) severely impairs boar reproductive function by inducing oxidative stress and inflammatory responses, while lycopene (LYC), as a potent antioxidant, exerts a potential protective effect on the male reproductive system. This study aimed to clarify the mechanism underlying LYC-mediated alleviation of HS-induced decline in semen quality in Rongchang boars, identify the most affected tissues, and explore its regulatory role in the Nrf2 (Nuclear factor E2-related factor 2) pathway. A total of 18 Rongchang boars with an initial body weight of 15.81 ± 1.07 kg were randomly assigned to three groups (6 boars per group): the control group (CON, 26 ± 1 °C), the heat stress group (HS, exposed to 35 ± 1 °C for 8 h daily), and the heat stress + 100 mg/kg lycopene group (HS + LYC). After 28 days of adaptive feeding and 14 days of HS treatment, samples were collected for semen quality analysis, testicular histological analysis, antioxidant index detection, transcriptome analysis, Nrf2 pathway detection, and inflammatory index detection. The results showed that HS significantly increased the sperm abnormality rate (

Indexed as

boarheat stresslycopeneNrf2 pathwaysemen qualitytissue-specific protection

Identifiers

PMID41750625
PMCPMC12938134

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.