Evidence map›Paper›PMID 41751343›Full record

ArticleBiomedicines2026

An Artificial Intelligence-Driven Multimorbidity Framework Reveals a Shared Metabolic and Immune Core Across Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia.

Meghna R Iyer, Benjamin Zhao, Xin He, David Camacho, Zihan Wei, Jennifer Deng, Cassie S Mitchell

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meghna R IyerLaboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University School of Medicine, Atlanta, GA 30332, USA.
Benjamin ZhaoLaboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University School of Medicine, Atlanta, GA 30332, USA.ORCID 0009-0008-3039-3235
Xin HeLaboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University School of Medicine, Atlanta, GA 30332, USA.
David CamachoLaboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University School of Medicine, Atlanta, GA 30332, USA.
Zihan WeiLaboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University School of Medicine, Atlanta, GA 30332, USA.
Jennifer DengLaboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University School of Medicine, Atlanta, GA 30332, USA.
Cassie S MitchellLaboratory for Pathology Dynamics, Department of Biomedical Engineering, Georgia Institute of Technology & Emory University School of Medicine, Atlanta, GA 30332, USA.ORCID 0000-0002-5472-6355

Funding

Integrative predictive medicine to identify disease causes, develop cures, and optimize patient careR35GM152245 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI Cassie S Mitchell · 2024 to 2026
$1.1M
Chan Zuckerberg Initiative 253558National Science Foundation 1944247NIH HHS R35GM152245NIH HHS U19AG056169
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer’s diseaseamyotrophic lateral sclerosisartificial intelligencefrontotemporal dementiaknowledge graphmachine learningmetabolic dysfunctionmultimorbidityneurodegenerationneuroinflammation

Identifiers

PMID41751343
PMCPMC12938555

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.