Evidence map›Paper›PMID 41751431›Full record

ArticleCurrent issues in molecular biology2026

T174M-M235T

Jorge H Portillo-Gallo, Jorge Manuel Sánchez-González, Ana Miriam Saldaña-Cruz, Martha Rocío Hernández-Preciado, Luis Arturo Camacho-Silvas, Verónica Michelle Ledesma-Martínez, Héctor Alfonso Gómez-Rodríguez, Jhonathan Cárdenas-Bedoya, Ingrid Patricia Dávalos-Rodríguez, Rafael Franco-Santillán and 1 more

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jorge H Portillo-GalloInstituto Nacional de Aprendizaje, Habilidades e Investigación de las Ciencias (INAHIC), Diana Natura H1, Zapopan ZC 45221, JA, Mexico.ORCID 0000-0003-4902-0072
Jorge Manuel Sánchez-GonzálezInstituto Nacional de Aprendizaje, Habilidades e Investigación de las Ciencias (INAHIC), Diana Natura H1, Zapopan ZC 45221, JA, Mexico.ORCID 0000-0003-1942-0163
Ana Miriam Saldaña-CruzInstituto de Terapia Experimental y Clínica (INTEC), Departamento de Farmacología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada 950, Colonia Independencia, Guadalajara ZC 44340, JA, Mexico.ORCID 0000-0003-2272-9612
Martha Rocío Hernández-PreciadoDepartamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada 750, Puerta 1B Edificio N, Colonia Independencia, Guadalajara ZC 44340, JA, Mexico.
Luis Arturo Camacho-SilvasFacultad de Medicina y Ciencias Biomédicas, Universidad Autónoma de Chihuahua, Circuito Universitario 31109, Campus II, Chihuahua ZC 31512, CH, Mexico.ORCID 0000-0002-5218-4118
Verónica Michelle Ledesma-MartínezLaboratorio Clínico, Hospital Ángeles Andares, Calle Universidad 200, Zapopan ZC 45116, JA, Mexico.
Héctor Alfonso Gómez-RodríguezDepartamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada 750, Puerta 1B Edificio N, Colonia Independencia, Guadalajara ZC 44340, JA, Mexico.
Jhonathan Cárdenas-BedoyaDepartamento de Disciplinas Filosófico, Metodológicas e Instrumentales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada 750, Puerta 1B Edificio N, Colonia Independencia, Guadalajara ZC 44340, JA, Mexico.ORCID 0000-0002-0244-9464
Ingrid Patricia Dávalos-RodríguezDivisión de Genética, Centro de Investigación Biomédica de Occidente, Delegación Jalisco, Instituto Mexicano del Seguro Social, Sierra Mojada 800, Colonia Independencia, Guadalajara ZC 44340, JA, Mexico.
Rafael Franco-SantillánDepartamento de Patología Clínica y Molecular, Instituto NIDIAC, Cobalto 2, Ciudad Industrial, Durango ZC 34208, DG, Mexico.
María Cristina Morán-MoguelFederación Mexicana de Patología Clínica y Medicina de Laboratorio, Av. Cuauhtémoc 330, Colonia Doctores ZC 06720, CDMX, Mexico.ORCID 0000-0001-6458-9617

Funding

Fondo Sectorial de Investigación en Servicios de Salud. CONACyT. 2013-01-201251.
6 · The paper itself

Abstract

Pre-eclampsia is a Hypertensive Disorder of Pregnancy (HDP) characterized by hypertension and proteinuria, affecting 2-8% of pregnancies worldwide and constituting a major public health concern. Genes of the renin-angiotensin system have been investigated as potential causative factors, but inconclusive results have been obtained. The objective of this pilot study is to evaluate the possible contribution of alleles, genotypes or haplotypes of two single-nucleotide polymorphisms (SNPs) T174M (rs4762) and M235T (rs699) in

Indexed as

AGT geneAGT polymorphismshaplotypesM235Tpre-eclampsiasingle nucleotide polymorphismsSNPsT174M

Identifiers

PMID41751431
PMCPMC12939915

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.