Evidence map›Paper›PMID 41751768›Full record

ReviewInternational journal of molecular sciences2026

Linear Epitope-Mediated Immunological Cross-Reactivity in Livestock Product Allergens.

Pengmei An, Yanjun Cong

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Immunodominant IgM Epitopes of theInternational journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pengmei AnCollege of Food and Health, Beijing Technology and Business University, Beijing 100048, China.ORCID 0009-0006-4300-0387
Yanjun CongCollege of Food and Health, Beijing Technology and Business University, Beijing 100048, China.ORCID 0000-0003-1473-2440

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linear epitopes, comprising continuous amino acid sequences, are critically implicated in the immunological cross-reactivity of livestock products owing to their stability during food processing. This paper aims to comprehensively review linear epitope-mediated cross-allergic reactions in major livestock products, including milk, eggs, and meat. Furthermore, this review systematically delineates the pathophysiological mechanisms underlying classical cross-allergic reactions, including α-Gal syndrome and avian egg syndrome, while addressing novel cross-reactive allergens, such as the thermostable poultry meat allergen Gal d 7 and the egg-milk cross-reactive protein α-vitellin, alongside their respective linear B-cell epitope profiles. Finally, this study summarizes the roles of these cross-reactive allergens in precise diagnosis and targeted therapy, providing a theoretical basis for future in-depth research on food cross-allergenic mechanisms.

Indexed as

AllergensEpitopesEpitopes, B-LymphocyteFood HypersensitivityLivestockAnimalsCross ReactionsHumansAllergensEpitopesEpitopes, B-Lymphocyteallergenscross-reactivitylinear epitopeslivestock products

Identifiers

PMID41751768
PMCPMC12940488

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.