Evidence map›Paper›PMID 41751802›Full record

ArticleInternational journal of molecular sciences2026

Transcriptomic Profiling of MicroRNA and Non-Coding RNA from Whole Blood of African Americans with MASLD.

Tanmoy Mondal, Brent E Korba, Christopher A Loffredo, Coleman I Smith, Ruth Quartey, Jasneet Sahota, Gemeyel Moses, Charles D Howell, Gail Nunlee-Bland, Zaki A Sherif and 1 more

Abstract read
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In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Tanmoy MondalDepartment of Biology, Howard University, Washington, DC 20059, USA.ORCID 0000-0001-6542-5163
Brent E KorbaDepartment of Biology, Howard University, Washington, DC 20059, USA.
Christopher A LoffredoDepartment of Oncology, Georgetown University, Washington, DC 20057, USA.
Coleman I SmithMedStar Georgetown Transplant Institute, Georgetown University School of Medicine, Washington, DC 20007, USA.
Ruth QuarteyDepartment of Internal Medicine, College of Medicine, Howard University, Washington, DC 20059, USA.
Jasneet SahotaDepartment of Biology, Howard University, Washington, DC 20059, USA.
Gemeyel MosesDepartment of Biology, Howard University, Washington, DC 20059, USA.ORCID 0000-0002-4896-8147
Charles D HowellDepartment of Internal Medicine, College of Medicine, Howard University, Washington, DC 20059, USA.ORCID 0000-0003-1188-0130
Gail Nunlee-BlandDepartments of Pediatrics and Child Health, College of Medicine, Howard University, Washington, DC 20059, USA.ORCID 0000-0001-6388-688X
Zaki A SherifDepartments of Biochemistry and Molecular Biology, College of Medicine, Howard University, Washington, DC 20059, USA.
Somiranjan GhoshDepartment of Biology, Howard University, Washington, DC 20059, USA.ORCID 0000-0002-5280-7418

Funding

National Institute of Health, USA MD007597-31-5959NCI NIH HHS CA262617-01
6 · The paper itself

Abstract

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD), is a growing health concern, yet the role of non-coding RNAs (ncRNAs), including microRNAs (miRNAs), in its pathogenesis remains poorly understood. In this pilot study, we aimed to identify significantly expressed miRNAs and ncRNAs and correlate transcriptomic patterns of the findings with previously identified coding gene expression profiles to explore potential regulatory mechanisms in MASLD. Participants were selected from an existing study population. We conducted transcriptomic profiling of miRNAs and other ncRNAs in whole-blood samples from African American (AA) individuals with MASLD and matched controls (

Indexed as

Black or African AmericanMicroRNAsNon-alcoholic Fatty Liver DiseaseRNA, UntranslatedTranscriptomeAdultFemaleGene Expression ProfilingGene Expression RegulationHumansMaleMiddle AgedPilot ProjectsMicroRNAsRNA, UntranslatedAfrican AmericansMASLDmicroRNAs (miRNAs)non-coding RNAs (ncRNAs)transcriptomics

Identifiers

PMID41751802
PMCPMC12940169

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.