Evidence mapPaperPMID 41751817Full record

SynthesisInternational journal of molecular sciences2026

Diagnostic Potential of Circulating miRNAs in Glioma: A Systematic Review and Meta-Analysis.

Aizere Khassenova, Zhamilya Seitkanova, Alissa Loskutova, Rostislav Bukasov, Olena Filchakova

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aizere KhassenovaBiology Department, School of Sciences and Humanities, Nazarbayev University, Kabanbay Batyr Ave., 53, Astana 010000, Kazakhstan.
Zhamilya SeitkanovaBiology Department, School of Sciences and Humanities, Nazarbayev University, Kabanbay Batyr Ave., 53, Astana 010000, Kazakhstan.
Alissa LoskutovaChemistry Department, School of Sciences and Humanities, Nazarbayev University, Kabanbay Batyr Ave., 53, Astana 010000, Kazakhstan.
Rostislav BukasovChemistry Department, School of Sciences and Humanities, Nazarbayev University, Kabanbay Batyr Ave., 53, Astana 010000, Kazakhstan.ORCID 0000-0002-7060-1632
Olena FilchakovaBiology Department, School of Sciences and Humanities, Nazarbayev University, Kabanbay Batyr Ave., 53, Astana 010000, Kazakhstan.

Funding

NAZARBAYEV UNIVERSITY (NU) Faculty Development Competitive Research Grant Program (FDCRGP) 040225FD4728
6 · The paper itself

Abstract

Gliomas are intracranial tumors characterized by limited diagnostics and treatment approaches. Blood-circulating miRNAs represent a regulatory class of molecules that change their expression under pathological conditions and can relatively easily be detected. The present study evaluates the diagnostic potential of blood-circulating miRNAs in glioma. All grades of gliomas are included in the analysis. The articles were retrieved from the PubMed, Web of Science and Scopus databases up to October 2025. The studies were considered to be eligible if they used glioma patients and healthy controls and compared their miRNA levels, indicating sensitivity and specificity values. Risk of bias was assessed using the QUADAS-2 tool. The collected data was pooled by the STATA 19.0 MP bivariate random effects model and indicated heterogeneity using the I

Indexed as

Biomarkers, TumorBrain NeoplasmsCirculating MicroRNAGliomaMicroRNAsHumansSensitivity and SpecificityBiomarkers, TumorCirculating MicroRNAMicroRNAsbiomarkersdiagnosticsglioblastomagliomamiRNA

Identifiers

PMID41751817
PMCPMC12941128

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.