ArticleInternational journal of molecular sciences2026
Study on the Threshold of Serum Ferritin Required for Erythropoiesis and Iron Sufficiency in Hemodialysis Patients.
Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Serum ferritin (Ft) reflects total body iron stores and serves as a reference indicator for iron supplementation. However, optimal Ft level remains unclear in hemodialysis (HD) patients. We previously reported that total body iron (TBI), a novel index defined as the sum of red blood cell iron and storage iron, increases during oral iron replacement therapy (OIRT) and remains stable once iron sufficiency is achieved. In this study, we analyzed data from 100 OIRT courses in 79 maintenance HD patients. We examined the relationship between changes in hemoglobin (Hb) and Ft (⊿Hb, ⊿Ft) at 4 and 7 months after the initiation of OIRT, during which TBI remained stable, to determine the Ft level required for erythropoiesis. At 7 months, compared with 4 months, mean Hb significantly decreased by 0.2 g/dL (
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