Evidence map›Paper›PMID 41751956›Full record

ArticleInternational journal of molecular sciences2026

Comprehensive Analysis of the Placenta-Cortex Transcriptomic Database Reveals a Neuroactive Ligand-Receptor Dysregulation After Prenatal Alcohol Exposure.

Camille Sautreuil, Maryline Lecointre, Céline Derambure, Carole Brasse-Lagnel, Gaël Nicolas, Sophie Gil, Daniel D Savage, Stéphane Marret, Florent Marguet, Bruno J Gonzalez and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Camille SautreuilUniversity Rouen Normandie, INSERM U1245, Team Epigenetics and Pathophysiology of Neurodevelopmental Disorders, 76183 Rouen, France.
Maryline LecointreUniversity Rouen Normandie, INSERM U1245, Team Epigenetics and Pathophysiology of Neurodevelopmental Disorders, 76183 Rouen, France.ORCID 0000-0003-1589-4097
Céline DerambureUniversity Rouen Normandie, INSERM U1245, Team Genetic Predisposition to Cancer, 76183 Rouen, France.ORCID 0000-0002-6722-5955
Carole Brasse-LagnelUniversity Rouen Normandie, INSERM U1245, Team Epigenetics and Pathophysiology of Neurodevelopmental Disorders, 76183 Rouen, France.ORCID 0000-0003-4370-2865
Gaël NicolasUniversity Rouen Normandie, INSERM U1245, Team Genomics for Brain Disorders, 76183 Rouen, France.ORCID 0000-0001-9391-7800
Sophie GilUniversité Paris Cité, INSERM UMR-S 1144, Optimisation Thérapeutique en Neuropsychopharmacologie, OTeN, F-75006 Paris, France.
Daniel D SavageDepartment of Neurosciences, School of Medicine, University of New Mexico, Albuquerque, NM 87106, USA.
Stéphane MarretUniversity Rouen Normandie, INSERM U1245, Team Epigenetics and Pathophysiology of Neurodevelopmental Disorders, 76183 Rouen, France.ORCID 0000-0002-2858-148X
Florent MarguetUniversity Rouen Normandie, INSERM U1245, Team Epigenetics and Pathophysiology of Neurodevelopmental Disorders, 76183 Rouen, France.ORCID 0000-0001-7306-0520
Bruno J GonzalezUniversity Rouen Normandie, INSERM U1245, Team Epigenetics and Pathophysiology of Neurodevelopmental Disorders, 76183 Rouen, France.ORCID 0000-0002-7176-1320
Anthony Falluel-MorelUniversity Rouen Normandie, INSERM U1245, Team Epigenetics and Pathophysiology of Neurodevelopmental Disorders, 76183 Rouen, France.ORCID 0000-0002-4081-6704

Funding

Agence Nationale de la Recherche AlcoBrainFondation de France AlcoBrainInserm UMR-1245Rouen University hospital AlcoBrainUniversité de Rouen Normandie UMR-1245
6 · The paper itself

Abstract

Neuroplacentology is an emerging field of research supporting that the placenta actively contributes to the fetal brain development through the release of bioactive molecules. Recent angiogenesis-focused data showed that prenatal alcohol exposure (PAE) disrupts inter-organ gene expression between the placenta and fetal cortex. The present study aimed to perform the first comprehensive and untargeted analysis of a murine placenta-cortex transcriptomic database of PAE. Gene lists from a recently

Indexed as

Cerebral CortexEthanolPlacentaPrenatal Exposure Delayed EffectsTranscriptomeAnimalsDatabases, GeneticFemaleGene Expression ProfilingLigandsMicePregnancyProtein Interaction MapsEthanolLigandsdiagnosisFASDneurodevelopmentneuroplacentologyneurovascular

Identifiers

PMID41751956
PMCPMC12940763

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.