Evidence map›Paper›PMID 41753100›Full record

ReviewJournal of clinical medicine2026

Patient Self-Inflicted Lung Injury in ARDS: From Physiological Concept to Clinical Syndrome.

Raffaele Merola, Patricia R M Rocco, Denise Battaglini

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raffaele MerolaAnesthesia and Intensive Care Medicine, Department of Critical Care, AORN Ospedali Dei Colli, 80131 Naples, Italy.ORCID 0000-0002-0159-1426
Patricia R M RoccoLaboratory of Pulmonary Investigation, Carlos Chagas Filho Institute of Biophysics, Federal University of Rio de Janeiro, Avenida Carlos Chagas Filho, s/n, Bloco G2-042, Ilha do Fundão, Rio de Janeiro 21941-902, Brazil.ORCID 0000-0003-1412-7136
Denise BattagliniDepartment of Surgical Sciences and Integrated Diagnostics (DISC), University of Genoa, 16132 Genova, Italy.ORCID 0000-0002-6895-6442

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In acute respiratory distress syndrome (ARDS), spontaneous breathing is often encouraged to preserve lung function, yet excessive patient-generated inspiratory effort can paradoxically worsen injury, a phenomenon termed patient self-inflicted lung injury (P-SILI). In mechanically heterogeneous lungs, uncontrolled effort amplifies regional stress, strain, and mechanical power, driving alveolar overdistension, cyclic recruitment-derecruitment,

Indexed as

acute respiratory distress syndrome (ARDS)mechanical ventilationpatient self-inflicted lung injury (P-SILI)respiratory physiologysedation

Identifiers

PMID41753100
PMCPMC12942290

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.