Evidence map›Paper›PMID 41753406›Full record

ArticleMaterials (Basel, Switzerland)2026

In Vitro Analysis of Heavy Metal Adsorption by Zeolite Skin Care Formulations Using a Quality by Design Approach.

Alessandro Nencioni, Michela Bulfoni, Emanuele Nencioni

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alessandro NencioniIBSA Institut Biochimique SA, Via del Piano 29, CH-6915 Pambio Noranco, Switzerland.
Michela BulfoniDepartment of Medicine, University of Udine, 33100 Udine, UD, Italy.ORCID 0000-0003-2646-4228
Emanuele NencioniBiofarma Group, Via Castelliere, 2, 33036 Mereto di Tomba, UD, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zeolites are microporous aluminosilicate minerals widely recognized for their adsorption and ion-exchange properties. Their capacity to capture toxic heavy metals has prompted growing interest in their use as anti-pollution agents in skin care formulations. This study investigates zeolite-based creams through an in vitro permeation test using Franz diffusion cells within a Quality by Design (QbD) framework. A 2 × 2 × 2 full factorial design was applied to evaluate the effects of three critical factors: membrane type (Strat-M

Indexed as

Franz diffusion cellheavy metal adsorptionQuality by Design (QbD)skin care formulationzeolite

Identifiers

PMID41753406
PMCPMC12942069

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.