Evidence map›Paper›PMID 41753563›Full record

ArticleMicroorganisms2026

Perinatal Antibiotic Timing Impairs Maternal IgG Transfer via FcRn and Shapes the Neonatal Gut Microbiome in Mice.

Yanan Ding, Ali Liu, Bingbing Ma, Huiqun Zhang, Chunmei Zhang, Junmin Li, Jincheng Han, Chuanxin Shi

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yanan DingCollege of Biology and Food, Shangqiu Normal University, Shangqiu 476000, China.
Ali LiuCollege of Biology and Food, Shangqiu Normal University, Shangqiu 476000, China.
Bingbing MaCollege of Biology and Food, Shangqiu Normal University, Shangqiu 476000, China.ORCID 0000-0002-8987-9968
Huiqun ZhangCollege of Biology and Food, Shangqiu Normal University, Shangqiu 476000, China.
Chunmei ZhangCollege of Biology and Food, Shangqiu Normal University, Shangqiu 476000, China.
Junmin LiCollege of Biology and Food, Shangqiu Normal University, Shangqiu 476000, China.
Jincheng HanCollege of Biology and Food, Shangqiu Normal University, Shangqiu 476000, China.
Chuanxin ShiCollege of Biology and Food, Shangqiu Normal University, Shangqiu 476000, China.ORCID 0000-0002-1750-0103

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perinatal antibiotic exposure poses a significant risk to maternal-offspring immune programming and infant gut microbiota development. This study investigated the time-specific effects of maternal cefoperazone sodium (CPZ) administration on IgG transfer and offspring gut microbiota in a murine model. Pregnant C57BL/6J mice were assigned to control (CON), gestational (G-CPZ), lactational (L-CPZ), and combined gestational/lactational (GL-CPZ) treatment groups. Results showed that all CPZ treatments significantly reduced IgG and its subtype levels in maternal serum, colostrum, and offspring serum (

Indexed as

FcRngut microbiotaIgG transferneonatal immunityperinatal antibiotic

Identifiers

PMID41753563
PMCPMC12943489

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.