Evidence map›Paper›PMID 41753787›Full record

ArticleMicroorganisms2026

Effectiveness of COVID-19 Vaccines Against Hospitalization and Severe Disease in Children with Diabetes Mellitus During Pandemic and Post-Pandemic Eras.

Laura G Coelho, Lilian M Diniz, Stella C Galante, Cristiane S Dias, Maria Christina L Oliveira, Enrico A Colosimo, Ana Cristina Simões E Silva, Fernanda N Duelis, Maria Eduarda T Bernardes, Daniela R Martelli and 4 more

Abstract read
In one paragraph

Article in Microorganisms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Laura G CoelhoHealth Sciences Postgraduate Program, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais (UFMG), R. Engenheiro Amaro Lanari 389/501, Belo Horizonte 30310-580, MG, Brazil.ORCID 0009-0001-2479-4429
Lilian M DinizHealth Sciences Postgraduate Program, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais (UFMG), R. Engenheiro Amaro Lanari 389/501, Belo Horizonte 30310-580, MG, Brazil.
Stella C GalanteHealth Sciences Postgraduate Program, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais (UFMG), R. Engenheiro Amaro Lanari 389/501, Belo Horizonte 30310-580, MG, Brazil.ORCID 0009-0002-5790-1136
Cristiane S DiasHealth Sciences Postgraduate Program, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais (UFMG), R. Engenheiro Amaro Lanari 389/501, Belo Horizonte 30310-580, MG, Brazil.ORCID 0000-0001-6559-3300
Maria Christina L OliveiraHealth Sciences Postgraduate Program, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais (UFMG), R. Engenheiro Amaro Lanari 389/501, Belo Horizonte 30310-580, MG, Brazil.ORCID 0000-0002-2511-6769
Enrico A ColosimoDepartment of Statistics, Federal University of Minas Gerais (UFMG), Belo Horizonte 31270-901, MG, Brazil.
Ana Cristina Simões E SilvaHealth Sciences Postgraduate Program, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais (UFMG), R. Engenheiro Amaro Lanari 389/501, Belo Horizonte 30310-580, MG, Brazil.ORCID 0000-0001-9222-3882
Fernanda N DuelisHealth Sciences Postgraduate Program, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais (UFMG), R. Engenheiro Amaro Lanari 389/501, Belo Horizonte 30310-580, MG, Brazil.ORCID 0009-0007-0981-4843
Maria Eduarda T BernardesHealth Sciences Postgraduate Program, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais (UFMG), R. Engenheiro Amaro Lanari 389/501, Belo Horizonte 30310-580, MG, Brazil.ORCID 0009-0000-4790-1955
Daniela R MartelliHealth Science/Primary Care Postgraduate Program, State University of Montes Claros (Unimontes), Montes Claros 39401-089, MG, Brazil.ORCID 0000-0002-3979-7497
Fabrício Emanuel S OliveiraHealth Science/Primary Care Postgraduate Program, State University of Montes Claros (Unimontes), Montes Claros 39401-089, MG, Brazil.ORCID 0000-0003-0164-1179
Hercílio Martelli-JuniorHealth Science/Primary Care Postgraduate Program, State University of Montes Claros (Unimontes), Montes Claros 39401-089, MG, Brazil.
Robert H MakDepartment of Pediatrics, Division of Pediatric Nephrology, University of California, San Diego, CA 92123, USA.
Eduardo A OliveiraHealth Sciences Postgraduate Program, Department of Pediatrics, School of Medicine, Federal University of Minas Gerais (UFMG), R. Engenheiro Amaro Lanari 389/501, Belo Horizonte 30310-580, MG, Brazil.ORCID 0000-0002-5642-7164

Funding

Fundação de Apoio a Pesquisa do Estado de Minas Gerais APQ-03205-24Fundação de Apoio a Pesquisa do Estado de Minas Gerais APQ-04839-24National Council for Scientific and Technological Development 405731/2023-0National Council for Scientific and Technological Development (CNPq) 301522/2025-1
6 · The paper itself

Abstract

Pediatric patients with SARS-CoV-2 infection are at an increased risk of severe disease and adverse outcomes. Nevertheless, comprehensive data on COVID-19 vaccine effectiveness (VE) in children with diabetes during the post-pandemic period remain limited. This study assessed the VE against severe COVID-19 outcomes during both the pandemic and post-pandemic phases in children with and without diabetes mellitus (DM). A cohort study based on population data was carried out, including all patients under 18 years of age with symptomatic SARS-CoV-2 infection as registered in the Brazilian national surveillance systems from February 2020 to June 2025. The main outcomes were hospitalization due to COVID-19 and severe illness, which included admission to the intensive care unit (ICU), need for invasive ventilation, and death. Utilizing a propensity score-matched cohort, we estimated the VE and the number needed to vaccinate (NNV) for a booster dose against these outcomes by comparing vaccinated and unvaccinated individuals, employing conditional logistic regression adjusted for confounding variables. The cohort comprised 3,730,007 pediatric patients with COVID-19, of whom 7675 (0.2%) had DM. At baseline, children with DM exhibited a significantly higher prevalence of hospitalization (11.2% vs. 2.0%), severe COVID-19 (6.4% vs. 0.6%), and mortality (1.9% vs. 0.1%) than those without DM (all

Indexed as

childrenCOVID-19diabetes mellituspost-pandemicvaccine effectiveness

Identifiers

PMID41753787
PMCPMC12942963

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.