Oxidative Balance Score Is Associated with Social Involvement and Weight-Adjusted Appendicular Skeletal Muscle Mass in Middle-Aged and Older Japanese Women.

Tamami Odai, Masakazu Terauchi, Yuka Enokuchi, Naoyuki Miyasaka

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Article in Nutrients, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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Authors and funding

4 authors.

Tamami OdaiDepartment of Women's Health, Institute of Science Tokyo, Yushima 1-5-45, Bunkyo, Tokyo 113-8510, Japan.ORCID 0009-0007-7007-2324

Masakazu TerauchiDepartment of Women's Health, Institute of Science Tokyo, Yushima 1-5-45, Bunkyo, Tokyo 113-8510, Japan.ORCID 0000-0001-5577-0094

Yuka EnokuchiDepartment of Women's Health, Institute of Science Tokyo, Yushima 1-5-45, Bunkyo, Tokyo 113-8510, Japan.

Naoyuki MiyasakaDepartment of Obstetrics and Gynecology, Institute of Science Tokyo, Yushima 1-5-45, Bunkyo, Tokyo 113-8510, Japan.ORCID 0000-0002-4713-8352

Funding

Japan Agency for Medical Research and Development (AMED) 25gk0210046h0001

6 · The paper itself

Abstract

backgroundThe oxidative balance score (OBS) is an indicator for assessing total oxidant status. This cross-sectional study aimed to investigate the relationships between OBS and factors associated with well-being among middle-aged and elderly women.

methodsDietary habits, lifestyle factors, and factors associated with well-being, including physical, mental, and social health, were assessed based on the first-visit medical records in 385 Japanese women. The OBS was calculated using pro-oxidant factors (fat, saturated fatty acids,

resultsAfter adjusting for age, menopausal status, and background factors, social engagement and weight-adjusted appendicular skeletal muscle mass (ASM/Wt) were found to be significantly associated with OBS (social involvement, odds ratio = 0.882, 95% confidence interval [CI] = 0.817-0.949,

conclusionsHigher oxidative stress was associated with a low level of social involvement and ASM/Wt. These findings indicate that oxidative balance is linked to social and physical aspects of well-being among middle-aged and older women. However, because of the cross-sectional design, causal relationships cannot be inferred, and the possibility of reverse causation should be considered.

Indexed as

Muscle, SkeletalOxidative StressSocial ParticipationAgedAntioxidantsBody Mass IndexBody WeightCross-Sectional StudiesEast Asian PeopleFemaleHumansJapanLife StyleMiddle AgedAntioxidantsmuscle healthoxidative stresssocial engagementwell-being

Identifiers

PMID41754205

DOI10.3390/nu18040688

PMCPMC12943278

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LicenceCC BY

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