Evidence map›Paper›PMID 41754449›Full record

ArticlePathogens (Basel, Switzerland)2026

The Use of Molecular Biology Methods to Evaluate the Activity of Different Topical Treatments Against Periodontal Pathogen Bacteria.

Alessia Pardo, Salma Hamzaoui, Annarita Signoriello, Elena Messina, Maria Del Mar Lleò, Gloria Burlacchini, Andrea Butera, Andrea Scribante, Giorgio Lombardo, Caterina Signoretto

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alessia PardoDentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Pediatrics and Gynecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0002-6466-9825
Salma HamzaouiDiagnostic and Public Health Department, University of Verona, 37134 Verona, Italy.
Annarita SignorielloDentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Pediatrics and Gynecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0002-9761-4046
Elena MessinaDentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Pediatrics and Gynecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0002-1268-5233
Maria Del Mar LleòDiagnostic and Public Health Department, University of Verona, 37134 Verona, Italy.
Gloria BurlacchiniDiagnostic and Public Health Department, University of Verona, 37134 Verona, Italy.
Andrea ButeraUnit of Orthodontics and Pediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0003-2457-4415
Andrea ScribanteUnit of Orthodontics and Pediatric Dentistry, Section of Dentistry, Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-2760-0124
Giorgio LombardoDentistry and Maxillo-Facial Surgery Unit, Department of Surgery, Dentistry, Pediatrics and Gynecology (DIPSCOMI), University of Verona, Piazzale L.A. Scuro 10, 37134 Verona, Italy.ORCID 0000-0003-3677-6831
Caterina SignorettoDiagnostic and Public Health Department, University of Verona, 37134 Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeriodontal disease results from a complex interaction between the microbial biofilm and the host immune response. The aim of this study was to evaluate and compare, in samples of dental plaque in periodontal patients, the presence of periodontal bacteria before and after two different non-surgical treatments: ozone (O

methodsMolecular biology techniques were used to estimate the effect of the two treatments on different periodontal pathogen microorganisms. The presence of

results

conclusionBoth agents were effective in reducing the presence of the periodontal pathogens in the dental pockets of patients affected by chronic periodontal diseases. In particular, HBX applied three times showed greater improvement compared to a single application.

Indexed as

BacteriaOzonePeriodontal DiseasesAdministration, TopicalBiofilmsDental PlaqueHumansMolecular BiologyPorphyromonas gingivalisOzonebacteriadesiccant agentperiodontal diseaseperiodontal pathogens

Identifiers

PMID41754449
PMCPMC12942802

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.