Evidence map›Paper›PMID 41754521›Full record

ArticleViruses2026

Targeting SARS-CoV-2 Main Protease: A Bacteria-Based Colorimetric Assay for Screening Natural Antiviral Inhibitors.

Shaza S Issa, Andrew A Zelinsky, Haidar J Fayoud, Roman R Zhidkin, Tatiana V Matveeva

Abstract read
In one paragraph

Article in Viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shaza S IssaDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0002-1690-0199
Andrew A ZelinskyLaboratory of Amyloid Biology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0003-2068-3024
Haidar J FayoudDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0002-7543-2655
Roman R ZhidkinDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.
Tatiana V MatveevaDepartment of Genetics and Biotechnology, St. Petersburg State University, 199034 St. Petersburg, Russia.ORCID 0000-0001-8569-6665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

SARS-CoV-2 main protease (M

Indexed as

Antiviral AgentsColorimetryCoronavirus 3C ProteasesProtease InhibitorsSARS-CoV-2beta-GalactosidaseDrug Evaluation, PreclinicalEscherichia coliHumans3C-like proteinase, SARS-CoV-2Antiviral Agentsbeta-GalactosidaseCoronavirus 3C ProteasesProtease Inhibitorscolorimetric assaycurrantE. coliMpro inhibitorspomegranate juicerhubarbSARS-CoV-2screening assayβ-galactosidase

Identifiers

PMID41754521
PMCPMC12944850

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.