Evidence map›Paper›PMID 41754779›Full record

ArticlePharmaceuticals (Basel, Switzerland)2026

Design and Synthesis of 4-Arylazo Pyrazole Carboxamides as Dual AChE/BChE Inhibitors: Kinetic and In Silico Evaluation.

Suleyman Akocak, Nebih Lolak, Hatice Esra Duran, Büşra Demir Çetinkaya, Hamada Hashem, Stefan Bräse, Cüneyt Türkeş

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Isolation, modification, structure-activity relationship (SAR) and molecular docking studies of isoflavones from Derris scandens as potent dual AChE/BuChE inhibitors.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Suleyman AkocakDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Adıyaman University, Adıyaman 02040, Türkiye.ORCID 0000-0003-4506-5265
Nebih LolakDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Adıyaman University, Adıyaman 02040, Türkiye.
Hatice Esra DuranDepartment of Medical Biochemistry, Faculty of Medicine, Kafkas University, Kars 36100, Türkiye.ORCID 0000-0003-2080-0091
Büşra Demir ÇetinkayaDepartment of Pharmaceutical Toxicology, Faculty of Pharmacy, Erzincan Binali Yıldırım University, Erzincan 24002, Türkiye.ORCID 0000-0002-9926-107X
Hamada HashemDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag 82524, Egypt.ORCID 0000-0002-8649-7534
Stefan BräseInstitute of Biological and Chemical Systems Functional Molecular Systems (IBCS-FMS), Karlsruhe Institute of Technology (KIT), Kaiserstrasse 12, 76131 Karlsruhe, Germany.ORCID 0000-0003-4845-3191
Cüneyt TürkeşDepartment of Biochemistry, Faculty of Pharmacy, Erzincan Binali Yıldırım University, Erzincan 24002, Türkiye.ORCID 0000-0002-2932-2789

Funding

the Research Fund of Adıyaman grant numbers ECZMAP/2023-0002 and ECZMAP/2023-0004).
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

acetylcholinesteraseADME/Tox. predictionarylazo derivativesbutyrylcholinesterasemolecular dockingmolecular dynamicspyrazole carboxamides

Identifiers

PMID41754779
PMCPMC12943507

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.