Evidence mapPaperPMID 41754952Full record

ArticlePharmaceutics2026

Development of Brimonidine-Loaded Ethosomes for Glaucoma: Investigation of Intraocular Pressure-Lowering Potential In Vivo.

Samet Özdemir, Ali Asram Sağıroğlu, Eslim Şen, Büşra Gelmez Yıldız, Laman Karimli, Meltem Ezgi Durgun Kılıç, Ali Riza Cenk Celebi, Yıldız Özsoy

Abstract read
In one paragraph

Article in Pharmaceutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Samet ÖzdemirDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul Health and Technology University, Istanbul 34445, Türkiye.ORCID 0000-0001-6212-2706
Ali Asram SağıroğluDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul University-Cerrahpasa, Istanbul 34500, Türkiye.ORCID 0000-0002-6960-6364
Eslim ŞenDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul University-Cerrahpasa, Istanbul 34500, Türkiye.ORCID 0009-0000-3535-4915
Büşra Gelmez YıldızDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul University-Cerrahpasa, Istanbul 34500, Türkiye.ORCID 0000-0002-4224-7453
Laman KarimliDepartment of Ophthalmology, School of Medicine, Acibadem Mehmet Ali Aydinlar University, Istanbul 34636, Türkiye.
Meltem Ezgi Durgun KılıçDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul Health and Technology University, Istanbul 34445, Türkiye.ORCID 0000-0001-5724-9809
Ali Riza Cenk CelebiDepartment of Ophthalmology, Faculty of Medicine, Istanbul Health and Technology University, Istanbul 34445, Türkiye.
Yıldız ÖzsoyDepartment of Pharmaceutical Technology, Faculty of Pharmacy, Istanbul University, Istanbul 34116, Türkiye.ORCID 0000-0002-9110-3704

Funding

Acibadem University Scientific Research Projects Coordination Unit THD-2024-2211
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brimonidine tartrateethosomesglaucomaHET-CAMintraocular pressureophthalmic drug delivery

Identifiers

PMID41754952
PMCPMC12944022

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.