Evidence map›Paper›PMID 41755155›Full record

ReviewSensors (Basel, Switzerland)2026

Graphene-Based Sensors and Biosensors Fabricated via Pulsed Laser Deposition for Chemical and Biological Threat Detection: A Comprehensive Roadmap.

Diogenes Kreusch Filho, Larissa Oliveira de Sá, Marcela Rabelo de Lima, Adriel Faddul Stelzenberger Saber, Fernando M Araujo-Moreira

Abstract readReview
In one paragraph

Review in Sensors (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Diogenes Kreusch FilhoPrograma de Pós-Graduação em Engenharia Nuclear, Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Urca, Rio de Janeiro 22290-270, Brazil.ORCID 0009-0004-6625-8546
Larissa Oliveira de SáPrograma de Pós-Graduação em Engenharia Nuclear, Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Urca, Rio de Janeiro 22290-270, Brazil.ORCID 0009-0008-9326-2283
Marcela Rabelo de LimaPrograma de Pós-Graduação em Engenharia Nuclear, Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Urca, Rio de Janeiro 22290-270, Brazil.ORCID 0009-0003-4353-3544
Adriel Faddul Stelzenberger SaberPrograma de Pós-Graduação em Engenharia Nuclear, Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Urca, Rio de Janeiro 22290-270, Brazil.ORCID 0009-0002-8725-8743
Fernando M Araujo-MoreiraPrograma de Pós-Graduação em Engenharia Nuclear, Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Urca, Rio de Janeiro 22290-270, Brazil.ORCID 0000-0002-5423-0405

Funding

Financiadora de Estudos e Projetos PDI-DQBRN Convênio FINEP-FAPEB Nº 01.22.0534.00
6 · The paper itself

Abstract

Graphene-based sensors and biosensors are attractive candidates for chemical and biological threat detection due to their high surface sensitivity, rapid transduction, and low-power operation, yet real-world deployment remains constrained by cross-sensitivity, interface instability in biosensing, and limited validation under operational conditions. This review consolidates key requirements for Chemical, Biological, Radiological, and Nuclear (CBRN) detection and proposes a structured roadmap to guide the transition from laboratory demonstrations to field-relevant sensing systems. The roadmap is explicitly modular and non-linear, integrating (i) qualitative research planning and gap analysis, (ii) computational screening via molecular docking as a hypothesis-generation tool with well-defined limitations, (iii) graphene electrode fabrication and functionalization using pulsed laser deposition (PLD) to enable tunable thickness/defect engineering and strong interface control, (iv) multiscale characterization combining laboratory methods with in situ/portable diagnostics, and (v) field-oriented performance evaluation focused on response time, stability, selectivity against industrial interferents, and false-positive/false-negative behavior. Iterative feedback loops connect all modules, enabling progressive refinement of material processing, recognition chemistry, and device architecture. By framing success in terms of technology-maturity progression and operational metrics, this roadmap provides a practical, defense-relevant framework for developing deployable graphene-based CBRN sensing platforms.

Indexed as

Biosensing TechniquesGraphiteLasersHumansGraphitebiosensorsCBRN defensechemical warfare agentsgraphenenanomaterialsorganophosphate nerve agentspulsed laser deposition

Identifiers

PMID41755155
PMCPMC12944267

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.