Evidence map›Paper›PMID 41755580›Full record

ArticleActas espanolas de psiquiatria2026

Dysbiosis in the Family nucleus of Children Diagnosed With Autism Spectrumin Mexico City.

Alma Delia Genis Mendoza, Lucero Nuncio-Mora, Venancio Sánchez, Vanessa Gonzalez, Humberto Nicolini

Abstract read
In one paragraph

Article in Actas espanolas de psiquiatria, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alma Delia Genis MendozaDr. Juan N. Navarro Children's Psychiatric Hospital, CONASAMA, Secretaria de Salud Secretary of Health, 14080 Mexico city, Mexico; Laboratory of Genomics of Psychiatric and Degenerative Diseases, National Institute of Genomic Medicine, Ministry of Health, 14610 Mexico city, Mexico.
Lucero Nuncio-MoraLaboratory of Genomics of Psychiatric and Degenerative Diseases, National Institute of Genomic Medicine, Ministry of Health, 14610 Mexico city, Mexico.
Venancio SánchezDr. Juan N. Navarro Children's Psychiatric Hospital, CONASAMA, Secretaria de Salud Secretary of Health, 14080 Mexico city, Mexico.
Vanessa GonzalezPharmacogenomics Laboratory, National Institute of Genomic Medicine, Ministry of Health, 14610 Mexico city, Mexico.
Humberto NicoliniLaboratory of Genomics of Psychiatric and Degenerative Diseases, National Institute of Genomic Medicine, Ministry of Health, 14610 Mexico city, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between the gut microbiome and Autism Spectrum Disorder (ASD) has been the subject of growing interest in scientific research. Research into the relationship between the gut microbiome and ASD has gained relevance in recent years as recent studies have identified significant differences in the gut microbiome abundance and composition in ASD children compared to neurotypical ones. However, little is known about the microbiome interplay, changes and relationship in parents and children with ASD, considering that they share a consistent environment. Charactering the microbiota of trio-type families with a child diagnosed with autism.

methodsThe hypervariable region of the 16s ribosomal gene was sequenced from stool samples from adolescents with ASD and their parents. The analysis was performed using various software programs, including QIIME2 and DADA2.

resultsIn this paper, we discuss this relationship in three families, and observed that the gut microbiome of the offspring with ASD is more similar to the mother's than the father's microbiome.

conclusionsThese observations could lead to the understanding of the potential heritability of the disorder through parental connectedness of the gut microbiome and eventually to the development of interventions aimed at modulating the gut microbiota to improve symptoms associated with ASD.

Indexed as

Autism Spectrum DisorderDysbiosisGastrointestinal MicrobiomeAdolescentChildFemaleHumansMaleMexico

Identifiers

PMID41755580
PMCPMC12946731

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.