Evidence map›Paper›PMID 41756081›Full record

SynthesisFrontiers in public health2026

The effects of traditional mind-body exercises on cognitive function in neurodegenerative diseases or prodromal cognitive decline: a meta-analysis.

Xin Liu, Cai Cui, Jiacan Lv, Yinhang Zhang

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xin LiuCollege of Physical Education, Yangzhou University, Yangzhou, China.
Cai CuiArts and Physical Education Department, Henan Technical College of Construction, Zhengzhou, China.
Jiacan LvDepartment of Social Sports, Henan Sport University, Zhengzhou, China.
Yinhang ZhangCollege of Physical Education, Yangzhou University, Yangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The meta-analysis aimed to systematically assess the influence of traditional mind-body exercise (TMBE), including taichi, baduanjin, wuqinxi, and yoga, on cognitive functioning and related cognitive decline for patients with neurodegenerative diseases (NDDs) or Prodromal Cognitive Decline. Methods: Randomized controlled trials (RCTs) were published until October 19, 2025, as determined by searching PubMed, Cochrane Library, Web of Science, and Embase. The study population included adults with AD and PD, including those at prodromal stages, such as MCI and SCD. The interventions were a TMBE group and a control group. The primary outcome was overall cognitive functioning score, which was measured using the MMSE or MoCA, and secondary outcomes included executive function, memory, attention and language. Data were analyzed using random effects models and quality assessed with the Cochrane Risk of Bias Tool. Results: Twenty-one RCTs were included, with the total sample size varying according to outcome metrics. TMBE showed significant improvement in overall cognitive functioning (MMSE: MD = 0.65, 95% CI: 0.20 to 1.09, Conclusion: TMBE has demonstrated the ability to contribute to improvement of overall and specific cognitive functions in individuals diagnosed with NDDs or Prodromal Cognitive Decline. These trainings offer a promising non-pharmacological intervention strategy that is safe, reliable, and multi-targeted to improve cognitive impairment in this population. Systematic review registration: PROSPERO - International prospective register of systematic reviews Unique identifier: CRD420251106629, https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD420251106629.

Indexed as

CognitionCognitive DysfunctionMind-Body TherapiesNeurodegenerative DiseasesCognitive EnhancementHumansProdromal SymptomsRandomized Controlled Trials as Topicattentioncognitive functionexecutive functionlanguagememoryneurodegenerative diseasestraditional mind-body exercises

Identifiers

PMID41756081
PMCPMC12932201

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.