Peripheral blood CD4

Objective: This study aims to evaluate the association between peripheral blood CD4 Methods: A retrospective analysis was conducted on patients diagnosed with hematogenous disseminated pulmonary tuberculosis accompanied by intracranial parenchymal tuberculomas. Patients were categorized into two groups based on MRI findings: those demonstrating perilesional edema (edematous type) and those without (non-edematous type). Demographic data, clinical symptoms, peripheral blood T-lymphocyte subsets, and additional MRI features were compared between the two groups. Results: Among 144 patients included in the analysis, 56 were classified into the edematous group and 88 into the non-edematous group. The frequency of headache was higher in the edematous group (60.7%) compared to the non-edematous group (40.9%). The median age was lower in the edematous group [27.0 years (IQR: 20.8, 42.0)] relative to the non-edematous group [33.5 years (IQR: 24.0, 51.0)]. A higher proportion of female patients was also observed in the edematous group (55.4%), compared to the non-edematous group (35.2%). Univariate analysis indicated that female sex, elevated peripheral blood CD3 Conclusion: In patients with hematogenous disseminated pulmonary tuberculosis and concurrent intracranial tuberculomas, higher peripheral CD4 + T-lymphocyte counts are independently associated with the presence of perilesional edema and a greater likelihood of ring-like enhancement on MRI.