Evidence map›Paper›PMID 41756213›Full record

ArticleBrain communications2026

Increased cerebrospinal fluid YKL-40 concentration in hip fracture patients with delirium.

Thea Berntsen, Kaj Blennow, Henrik Zetterberg, Ingrid Fæhn Brekke, Mathias Nikolai Petersen Hella, Tom Tarjei Lian, Lene B Solberg, Christian Thomas Pollmann, Adi Karabeg, Olav Tobias Ødegaard and 6 more

Abstract read
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In one paragraph

Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Thea BerntsenOslo Delirium Research Group, Institute of Clinical Medicine, University of Oslo, Oslo 0318, Norway.ORCID https://orcid.org/0009-0001-0015-9359
Kaj BlennowDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal S-431 80, Sweden.
Henrik ZetterbergDepartment of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal S-431 80, Sweden.ORCID https://orcid.org/0000-0003-3930-4354
Ingrid Fæhn BrekkeDepartment of Anaesthesiology, Oslo University Hospital, Oslo 0424, Norway.
Mathias Nikolai Petersen HellaDepartment of Geriatric Medicine, Stavanger University Hospital, Stavanger 4011, Norway.
Tom Tarjei LianDepartment of Orthopaedic Surgery, Bærum Hospital, Vestre Viken Hospital Trust, Gjettum 1346, Norway.
Lene B SolbergDivision of Orthopaedic Surgery, Oslo University Hospital, Oslo 0424, Norway.
Christian Thomas PollmannDepartment of Orthopaedic Surgery, Akershus University Hospital, Lørenskog 1478, Norway.
Adi KarabegDepartment of Orthopaedic Surgery, Akershus University Hospital, Kongsvinger 2212, Norway.
Olav Tobias ØdegaardDepartment of Anaesthesiology, Akershus University Hospital, Kongsvinger 2212, Norway.
Marius MyrstadDepartment of Internal Medicine, Bærum Hospital, Vestre Viken Hospital Trust, Gjettum 1346, Norway.
Kristian SydnesDepartment of Surgery and Anaesthesia, Unit for Orthopaedic Surgery, Diakonhjemmet Hospital, Oslo 0319, Norway.
Roy Bjørkholt OlsenDepartment of Anaesthesiology and Intensive Care, Sørlandet Hospital, Arendal 4838, Norway.
Torgeir Bruun WyllerOslo Delirium Research Group, Institute of Clinical Medicine, University of Oslo, Oslo 0318, Norway.
Leiv Otto WatneOslo Delirium Research Group, Institute of Clinical Medicine, University of Oslo, Oslo 0318, Norway.
Bjørn Erik NeerlandOslo Delirium Research Group, Institute of Clinical Medicine, University of Oslo, Oslo 0318, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The underlying mechanisms of the neuropsychiatric syndrome delirium are still unknown, but neuroinflammation is a central hypothesis. Chitinase-3-like-protein-1 (YKL-40/

Indexed as

Alzheimer’s diseaseCSF biomarkersdeliriumneuroinflammationYKL-40

Identifiers

PMID41756213
PMCPMC12932948

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.