ArticleFrontiers in medicine2026
Association between the C-reactive protein to albumin ratio and unplanned readmission in ulcerative colitis: insights from a cohort study.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Objective: This study aimed to investigate the association between the C-reactive protein to albumin ratio (CAR) and unplanned readmissions in patients with ulcerative colitis (UC) and to evaluate its potential value as a predictive indicator. Methods: This study included 412 patients with UC who were hospitalized at the Affiliated Hospital of Shandong University of Traditional Chinese Medicine between June 2017 and June 2024. Cox proportional hazards models were used to evaluate the relationship between CAR, C-reactive protein (CRP), albumin (ALB), and unplanned readmission in patients with UC. Kaplan-Meier survival curves were plotted to analyze the differences in unplanned readmission rates across different value ranges. Restricted Cubic Splines (RCS) were employed to explore the dose-response relationship between these three variables and unplanned readmissions. Additionally, a subgroup analysis was conducted to evaluate the applicability of the model across different populations. The predictive performance of CAR was assessed using Receiver Operating Characteristic analysis. Results: During the 1-year follow-up, the unplanned readmission rate among patients with UC was 27.43%. After adjusting for potential confounders, each 1-unit increase in CAR was associated with a 126.9% higher risk of unplanned readmission. Kaplan-Meier survival curves demonstrated significant differences in unplanned readmission rates among UC patients stratified by CAR, CRP, and ALB quartiles (log-rank test, Conclusion: Elevated CAR levels were significantly correlated with increased rates of unplanned readmissions, suggesting its potential as an independent prognostic indicator for patients with UC.
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