Evidence map›Paper›PMID 41756526›Full record

ArticleMaterials today. Bio2026

Wet-adhesive metabolic hydrogel for osteoimmune-guided extraction socket healing.

Zifan Zhao, Jing Zhang, Hu Chen, Xu Zhang, Yuchun Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zifan ZhaoCenter of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, NHC Key Laboratory of Digital Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing Key Laboratory of Intelligent Biomanufacturing and Regeneration for Craniofacial Tissues, Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, Beijing, 100081, China.
Jing ZhangState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China.
Hu ChenCenter of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, NHC Key Laboratory of Digital Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing Key Laboratory of Intelligent Biomanufacturing and Regeneration for Craniofacial Tissues, Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, Beijing, 100081, China.
Xu ZhangCenter of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, NHC Key Laboratory of Digital Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing Key Laboratory of Intelligent Biomanufacturing and Regeneration for Craniofacial Tissues, Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, Beijing, 100081, China.
Yuchun SunCenter of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, NHC Key Laboratory of Digital Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing Key Laboratory of Intelligent Biomanufacturing and Regeneration for Craniofacial Tissues, Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, Beijing, 100081, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dynamic wet interfaces, exemplified by tooth extraction sockets, demand dressings that can maintain firm adhesion despite constant salivary flushing, suction, and mastication while actively guiding tissue regeneration. Conventional hemostatic materials detach easily under these forces, destabilizing clots and impairing healing. Here, we develop a photocurable wet-adhesive metabolic hydrogel (WAM-Gel) that integrates interfacial stability with bioinstructive metabolic signaling. The hydrogel is formed from

Indexed as

Dynamic wet interfacesMetabolic hydrogelOsteoimmune regenerationWet adhesionβ-hydroxybutyrate (BHB)

Identifiers

PMID41756526
PMCPMC12933753

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.