Extranodal marginal zone lymphoma presenting as a skin-based breast finding detected on screening mammography.

Yu-Soon Aileen Park, David J Supeck, Alan Zhu, Laura Harper, Richard E Sharpe

Abstract readCase Reports

In one paragraph

Article in Radiology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

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0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Soon Aileen ParkDivision of Breast Imaging and Intervention, Mayo Clinic Arizona, 5881 E. Mayo Blvd, Phoenix, AZ 85054, USA.

David J SupeckDivision of Breast Imaging and Intervention, Mayo Clinic Arizona, 5881 E. Mayo Blvd, Phoenix, AZ 85054, USA.

Alan ZhuMayo Clinic Alix School of Medicine, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA.

Laura HarperDivision of Breast Imaging and Intervention, Mayo Clinic Arizona, 5881 E. Mayo Blvd, Phoenix, AZ 85054, USA.

Richard E SharpeDivision of Breast Imaging and Intervention, Mayo Clinic Arizona, 5881 E. Mayo Blvd, Phoenix, AZ 85054, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extranodal marginal zone lymphoma (EMZL) of the breast is rare and may mimic benign skin lesions at screening. We report a 72-year-old woman with a new superficial mass on screening mammography. Tangential views and ultrasound localized the abnormality to the dermis/subdermis, and ultrasound-guided biopsy revealed a low-grade B cell lymphoma with plasmacytic differentiation. Staging with PET/CT, a skin punch biopsy of a cutaneous shoulder lesion, and bone marrow biopsy confirmed disseminated disease, consistent with stage IV EMZL. This case underscores practical imaging steps, strategies, and differential diagnostic considerations to correctly identify skin-based findings and avoid misclassification. When appearances are new or atypical, particularly without a visible cutaneous correlate, tissue sampling is warranted to exclude malignancy, including dermal lymphoma.

Indexed as

BI‑RADSBreast lymphomaBreast ultrasoundDermal lesionsExtranodal marginal zone lymphomaTangential mammography

Identifiers

PMID41756546

DOI10.1016/j.radcr.2026.01.060

PMCPMC12934220

What Socratic holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.