Evidence map›Paper›PMID 41756773›Full record

ArticleChemical & biomedical imaging2026

Dual-Emission Fluorescent Probe for Simultaneous Visualization of Monoamine Oxidase A and Lysyl Oxidase in Alzheimer's Disease Cell Models.

Yanyan Chen, Xiuxiu Wang, Wei Wei, Ling Zhang, Jing Zhao, Yong Qian

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical & biomedical imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yanyan ChenSchool of Basic Medical Sciences, Hubei University of Medicine, Shiyan, Hubei 442000, China.
Xiuxiu WangState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210023, Nanjing, China.
Wei WeiState Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 210023, Nanjing, China.ORCID https://orcid.org/0000-0003-0845-0527
Ling ZhangJiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Public Experimental Research Center, Xuzhou Medical University, Xuzhou 221002, China.ORCID https://orcid.org/0000-0001-8140-5840
Jing ZhaoState Key Laboratory of Coordination Chemistry, Chemistry and Biomedicine Innovation Center (ChemBIC), School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.ORCID https://orcid.org/0000-0001-5177-5699
Yong QianState Key Laboratory of Microbial Technology, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, School of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China.ORCID https://orcid.org/0000-0003-3788-3575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoamine oxidase A (MAO-A) and lysyl oxidase (LOX) are two distinct amine oxidases that play crucial roles in many neurodegenerative diseases. Despite their similar enzymatic nature, their spatial distribution in different diseases and potential synergistic effects are poorly understood, partly due to the technical difficulties in detecting them concurrently. Herein, we designed and synthesized a series of dicyanoisophorone-based fluorescent probes,

Indexed as

Alzheimer’s diseasedual-emission fluorescent probehigh-throughput screeninglysyl oxidasemonoamine oxidase A

Identifiers

PMID41756773
PMCPMC12933484

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.