ArticleEuropean journal of gastroenterology & hepatology2026
Accuracy of a new innovative column-free miniaturized gas-mass spectrometer compared with a classic gas-mass spectrometer to diagnose and monitor Helicobacter pylori infection: a prospective single blind study.
Article in European journal of gastroenterology & hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Effectiveness of a Multicomponent Formulation: A Prospective Observational Study in Patients with Gastroesophageal Reflux Symptoms.Pharmaceuticals (Basel, Switzerland) · 2026Article
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Authors and funding
16 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundHelicobacter pylori (H. pylori) is one of the most common bacterial infections, and it causes chronic gastritis, peptic ulcers, gastric mucosa-associated lymphoid tissue lymphoma, and gastric cancer. H. pylori infection can be essentially detected by invasive [i.e. requiring an upper gastrointestinal endoscopy (UGE)], and noninvasive techniques. The principle of the urea breath test exploits the abundant quantities of urease produced by H. pylori. Recently, advances in the field of micro-electromechanical systems and nano-electromechanical systems have been proposed. This study aimed to evaluate the accuracy of this new miniaturized column-free portable gas-mass spectrometry (GMS) test compared with the standard GMS to diagnose H. pylori infection before and after eradication therapy.
methodsConsecutive patients never treated for H. pylori infection and referred to our unit to perform a UGE between April and November 2024 were evaluated for this blind prospective trial. Patients' samples were analysed with both methods and data were compared.
resultsA total of 28 patients were enrolled and 92 were H. pylori positive. The data obtained from the two tests were compared, and no statistically significant difference was observed. DISCUSSION: Our experience highlights the potential for introducing new diagnostic tools that are less demanding in terms of cost and labour, without compromising diagnostic accuracy. To our knowledge, this is the first time that an innovative diagnostic tool proves to be as compact and as reliable; for this reason, it deserves to be implemented in clinical practice.
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