Evidence map›Paper›PMID 41758376›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Efficacy of low-concentration nitrous oxide gas anesthesia in routine cataract microsurgeries.

Kaori Morii, Kotaro Ishigami, Shinji Miura, Ritsuko Fujiwara, Azusa Akashi

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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kaori MoriiMorii Eye Clinic, Ueda Bild.2F,1-6-9 Mikagenakamachi, Higashi Nada, Kobe City, 658-0054, Hyogo Prefecture, Japan. k-morii@morii-eye.com.
Kotaro IshigamiMedical Corporation Yoshitokukai, Asagiri Hospital Ophthalmology, Akashi, Japan.
Shinji MiuraMedical Corporation Yoshitokukai, Asagiri Hospital Ophthalmology, Akashi, Japan.
Ritsuko FujiwaraMedical Corporation Yoshitokukai, Asagiri Hospital Ophthalmology, Akashi, Japan.
Azusa AkashiMedical Corporation Yoshitokukai, Asagiri Hospital Ophthalmology, Akashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

key messagesWHAT IS KNOWN : • Low-concentration nitrous oxide (LCNO) has been used in dentistry and some ophthalmic procedures and is believed to reduce anxiety and discomfort. • Evidence for its sedative effect in cataract microsurgery has largely relied on subjective patient reports rather than objective monitoring. WHAT IS NEW: • This study provides objective evidence, using bispectral index (BIS) monitoring, that LCNO induces mild sedation during routine cataract microsurgery. • LCNO significantly reduced the BIS values during surgery without causing clinically relevant changes in the vital signs or adverse events, supporting its safety and practicality for outpatient cataract surgery.

Indexed as

Anesthesia, InhalationAnesthetics, InhalationCataract ExtractionMicrosurgeryNitrous OxideAgedElectroencephalographyHumansMonitoring, IntraoperativeAnesthetics, InhalationNitrous OxideBispectral index (BIS)Conscious sedationElectroencephalographic monitoringInhalation analgesiaOoutpatient ophthalmic surgeryPatient comfort

Identifiers

PMID41758376
PMCPMC13197306

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.