Evidence map›Paper›PMID 41760798›Full record

ArticleLasers in medical science2026

Contrasting biological responses of gingival fibroblasts and keratinocyte to blue and violet light irradiation: implications for photobiomodulation use in the therapeutic management of periodontal disease.

Edward Gait-Carr, Monique Stoffels, Matthias Born, Haripriya Ramasamy, Ryan Moseley, Rachel J Waddington

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lasers in medical science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edward Gait-CarrSchool of Dentistry, Cardiff University, Cardiff, UK.
Monique StoffelsPhilips Oral Healthcare, Eindhoven, Netherlands.
Matthias BornPhilips Oral Healthcare, Eindhoven, Netherlands.
Haripriya RamasamySchool of Dentistry, Cardiff University, Cardiff, UK.
Ryan MoseleySchool of Dentistry, Cardiff University, Cardiff, UK.
Rachel J WaddingtonSchool of Dentistry, Cardiff University, Cardiff, UK. waddingtonrj@cardiff.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blue light is known to possess anti-microbial activity and has subsequently been proposed as a prophylactic treatment for the management of periodontal diseases. This study investigated the effect of blue light on cells from the soft gingival tissues within the oral cavity, with particular focus on its influence on the regulation of intracellular reactive oxygen species (ROS) production. Primary human gingival fibroblasts (pHGFs) and keratinocytes (pHGKs) were irradiated with either 457nm blue light or with 415nm violet light, with fluences 3-90 J/cm

Indexed as

FibroblastsGingivaKeratinocytesLow-Level Light TherapyPeriodontal DiseasesAcetylcysteineAntioxidantsBlue LightCell ProliferationCells, CulturedCell SurvivalHumansReactive Oxygen SpeciesAcetylcysteineAntioxidantsReactive Oxygen SpeciesAnti-oxidantsBlue lightCell viabilityFibroblastsGingival tissuesKeratinocytesPeriodontal diseaseReactive oxygen species

Identifiers

PMID41760798
PMCPMC12948868

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.