Evidence mapPaperPMID 41761211Full record

ReviewJournal of ovarian research2026

Herbal compounds in the treatment of polycystic ovary syndrome: an updated systematic review.

Sareh Dashti, Akram Ashouri, Narjes Bahri

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of ovarian research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07603505 (Effect of Nepeta Adenophyta Hedge Extract and Its Fractions on Polycystic Ovarian Syndrome), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07603505 phase1completednot on this map

Effect of Nepeta Adenophyta Hedge Extract and Its Fractions on Polycystic Ovarian Syndrome (PCOS)

TypeinterventionalSponsorJinnah Sindh Medical UniversityRan2025 to 2026Enrolled116ConditionsPolycystic Ovarian Syndrome (PCOS), Infertility, Metabolic DisordersArmsHerbal Formulation, Metformin XR, Metformin 750 mg and herbal formulation 500 mg
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sareh DashtiDepartment of Nursing and Midwifery, MMS.C., Islamic Azad University, Mashhad, Iran.ORCID http://orcid.org/0000-0003-2145-4290
Akram AshouriSocial Determinants of Health Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
Narjes BahriDepartment of Midwifery, Faculty of Medicine, Reproductive Health and Population Research Center, Gonabad University of Medical Sciences, Gonabad, Iran. nargesbahri@yahoo.com.ORCID http://orcid.org/0000-0002-1877-2573

Funding

Gonabad University of Medical Sciences 1649
6 · The paper itself

Abstract

backgroundPolycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age and one of the important causes of infertility due to a lack of ovulation.

objectiveGiven the consideration of herbal medicines in the treatment of this condition, this systematic review was conducted to investigate the effect of herbal compounds on the treatment of PCOS.

methodIn this systematic review, all original articles on human subjects investigating the effect of medicinal plants on PCOS that were published in Farsi or English were searched in Persian (Magiran and Scientific Information Database [SID]), and English (PubMed, Scopus, Google Scholar, and Web of Science) databases until August 2025. Exclusion criteria included duplicated publications and the unavailability of full-text articles. Search keywords included polycystic ovary syndrome, medicinal plants, systematic review, Traditional medicine, clinical trial, case-control study, female infertility, and women in Persian and their English equivalents. Of the primary 182 articles, the full text of 36 articles was screened based on the inclusion and exclusion criteria. Quality assessment, including risk of bias, was performed using the Jadad checklist. Finally, ten related articles were included in the study.

resultsOut of the 10 included studies (seven conducted in Iran and one each in China, the United States, and Oman, with a total of 548 participants) were included in the review. According to the study’s results, many herbal medicines, including green tea, caraway, black mint tea, ginger, Fennel, Nigella sativa, and bitter olive, could have a significant effect on improving biochemical, hormonal, and symptoms of PCOS.

conclusionsMedicinal plants, due to their antioxidant, anti-inflammatory, and hormone-regulatory properties, can be used to treat or reduce the complications of PCOS. However, the heterogeneity of the studies in terms of intervention, duration, and sample size requires further research to confirm the findings.

Indexed as

Herbal medicinesPolycystic ovary syndromeTraditional medicine

Identifiers

PMID41761211
PMCPMC13041406

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.