Evidence map›Paper›PMID 41761996›Full record

ReviewRevista de neurologia2026

Progress in the Treatment of Refractory Myasthenia Gravis.

Dan Liu, Jialing Mao, Jing Song, Manxia Wang

Abstract readReview
In one paragraph

Review in Revista de neurologia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dan LiuDepartment of Neurology, Lanzhou University Second Hospital, 730000 Lanzhou, Gansu, China.
Jialing MaoDepartment of Neurology, Lanzhou University Second Hospital, 730000 Lanzhou, Gansu, China.
Jing SongDepartment of Neurology, Lanzhou University Second Hospital, 730000 Lanzhou, Gansu, China.
Manxia WangDepartment of Neurology, Lanzhou University Second Hospital, 730000 Lanzhou, Gansu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myasthenia gravis (MG) is an autoantibody-mediated, cellular immune-dependent and complement system-involved autoimmune disorder characterized by acquired neuromuscular junction transmission dysfunction driven by genetic and environmental factors. Approximately 10% therapies such as cholinesterase inhibitors, glucocorticoids, and immunosuppressants, resulting in the development of refractory MG (RMG). The current emergence of new therapeutic strategies such as targeted biologics (e.g., complement inhibitors, Fc receptor (FcRn) antagonists, etc.), B-cell depletion therapy, and Chimeric Antigen Receptor (CAR)-T cell therapy contribute to the significant improvement in the clinical management of RMG. Accordingly, the present study systematically reviewed the treatment progress of RMG, aiming to provide evidence-based individualized treatment decision-making clinically, alleviate patients' pain, and explore future research directions.

Indexed as

Myasthenia GravisCholinesterase InhibitorsComplement Inactivating AgentsHumansImmunosuppressive AgentsCholinesterase InhibitorsComplement Inactivating AgentsImmunosuppressive AgentsCAR-T cell therapycomplement inhibitorsrefractory myasthenia gravistargeted therapy

Identifiers

PMID41761996
PMCPMC12958055

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.