Evidence map›Paper›PMID 41762285›Full record

ArticleEuropean journal of nutrition2026

Nutrient intake is associated with incident mental disorders: a population-based prospective cohort study.

Tingting Mao, Yifan Gou, Lina Qin, Yue Che, Weixuan Da, Yijia Li, Hanchi Wang, Jin Feng, Li Liu, Huan Liu and 4 more

Abstract read
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In one paragraph

Article in European journal of nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tingting Mao *Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.ORCID http://orcid.org/0009-0006-6138-4353
Yifan Gou *Key Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Lina QinKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Yue CheKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Weixuan DaKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Yijia LiKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Hanchi WangKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Jin FengKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Li LiuKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Huan LiuKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Bolun ChengKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Yumeng JiaKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Yan WenKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China.
Feng ZhangKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission, School of Public Health, Health Science Center, Xi'an Jiaotong University, No. 76 Yan Ta West Road, Xi'an, 710061, People's Republic of China. fzhxjtu@mail.xjtu.edu.cn.

Funding

Natural Science Basic Research Program of Shaanxi Province 2021JCW-08
6 · The paper itself

Abstract

backgroundPotential associations between nutrient intake and mental disorders was suggested, but remains unclear. We aimed to investigate the associations between dietary nutrient intake and three major mental disorders.

methodsWe analyzed 169,776 participants in the UK Biobank who had no prior diagnoses of depression, anxiety, or suicide from baseline (2006-2010) to 2020. Dietary intake was assessed via Oxford WebQ and adjusted using a nutrient residual model. As dietary data were self-reported, potential measurement error and recall bias may exist. Nutrient intake levels were categorized into tertiles. Mental disorder diagnoses were identified using the International Classification of Diseases, 10th Revision (ICD-10). Associations were examined using Cox proportional hazards models, with subgroup analyses by sex, body mass index and Townsend Deprivation Index.

resultsThe median follow-up period was 10.4 years. Over the follow-up period, 6637 (3.91%) participants developed depression, 6160 (3.63%) developed anxiety, and 447 (0.26%) attempted suicide. Intake of polyunsaturated fatty acids, fat, protein, fibre and carbohydrate were significantly associated with mental disorders. For example, inversely association was observed in n-3 fatty acids (HR 0.880, 95% CI 0.829-0.935) with depression; vegetable protein with anxiety (HR 0.820, 95% CI 0.771-0.872), and fat with suicide (HR 0.705, 95% CI 0.559-0.889). Subgroup analyses indicated these associations were significant only in women; notably, higher n-3 fatty acids were associated with lower depression risk (HR 0.819, 95% CI 0.760-0.882), but not in men.

conclusionNutrient intake was associated with depression, anxiety, and suicide, highlighting its potential as a predictive tool or prevention in mental health.

Indexed as

DietMental DisordersNutrientsAdultAgedAnxietyDepressionFemaleHumansIncidenceMaleMiddle AgedProportional Hazards ModelsProspective StudiesRisk FactorsUnited KingdomAnxietyDepressionFatty acidsMental disordersNutrients

Identifiers

PMID41762285

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.